Role of nitric oxide in the pathogenesis of muscular dystrophies: a "two hit" hypothesis of the cause of muscle necrosis (Q34465820)

2 August 2017

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title

Role of nitric oxide in the pathogenesis of muscular dystrophies: a "two hit" hypothesis of the cause of muscle necrosis (English)

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2 August 2017

Rando TA

1

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2 August 2017

1 November 2001

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Microscopy Research and Technique

2 August 2017

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2 August 2017

55

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2 August 2017

223-235

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2 August 2017

4

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Neuronal nitric oxide synthase localizes through multiple structural motifs to the sarcolemma in mouse myotubes

2 August 2017

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Animal models for muscular dystrophy: valuable tools for the development of therapies

21 January 2018

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Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

21 January 2018

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

21 January 2018

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Failure to Confirm a Vascular Cause of Muscular Dystrophy

21 January 2018

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Endogenous nitric oxide synthesis: biological functions and pathophysiology

21 January 2018

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Nitric oxide: a physiologic messenger molecule

21 January 2018

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Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy

21 January 2018

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Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains

21 January 2018

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Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy

21 January 2018

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Selective loss of sarcolemmal nitric oxide synthase in Becker muscular dystrophy

21 January 2018

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Molecular basis of muscular dystrophies.

21 January 2018

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Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy

21 January 2018

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Nitric oxide and oxygen radicals: a question of balance.

21 January 2018

1 reference

Guanylate cyclase and the .NO/cGMP signaling pathway

21 January 2018

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Dystrophin mutations predict cellular susceptibility to oxidative stress

21 January 2018

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Progressive muscular dystrophy in alpha-sarcoglycan-deficient mice

21 January 2018

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Disruption of the beta-sarcoglycan gene reveals pathogenetic complexity of limb-girdle muscular dystrophy type 2E

21 January 2018

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Segmental muscle fiber lesions after repetitive eccentric contractions.

21 January 2018

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Membrane abnormalities and Ca homeostasis in muscles of the mdx mouse, an animal model of the Duchenne muscular dystrophy: a review

21 January 2018

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Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies

21 January 2018

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Gamma-sarcoglycan deficiency leads to muscle membrane defects and apoptosis independent of dystrophin

21 January 2018

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Muscle degeneration without mechanical injury in sarcoglycan deficiency

21 January 2018

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Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good: a personal view of recent controversies

21 January 2018

1 reference

Targeted disruption of the neuronal nitric oxide synthase gene.

21 January 2018

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide

21 January 2018

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Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species.

21 January 2018

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Vitamin E and muscle diseases.

21 January 2018

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Duchenne dystrophy. I. Morphometric study of the muscle microvasculature.

21 January 2018

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alpha1-syntrophin gene disruption results in the absence of neuronal-type nitric-oxide synthase at the sarcolemma but does not induce muscle degeneration

21 January 2018

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Nitric oxide in skeletal muscle

21 January 2018

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Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

21 January 2018

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Protein-protein interactions controlling nitric oxide synthases

21 January 2018

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Sarcospan-deficient mice maintain normal muscle function

21 January 2018

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Capillary Circulation and Morphology in Duchenne Muscular Dystrophy

21 January 2018

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Effects of contractile activity on muscle damage in the dystrophin-deficient mdx mouse

21 January 2018

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Accumulation of calcium by normal and dystrophin-deficient mouse muscle during contractile activity in vitro

21 January 2018

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How does dystrophin deficiency lead to muscle degeneration?--evidence from the mdx mouse

21 January 2018

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Decreased osmotic stability of dystrophin-less muscle cells from the mdx mouse

21 January 2018

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Oxidative stress and muscular dystrophy

21 January 2018

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Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle

21 January 2018

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From dystrophinopathy to sarcoglycanopathy: evolution of a concept of muscular dystrophy

21 January 2018

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Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

21 January 2018

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Dystrophin protects the sarcolemma from stresses developed during muscle contraction

21 January 2018

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The dystrophin-glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies

21 January 2018

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Peroxidation of brain lipids in vitro: nitric oxide versus hydroxyl radicals.

21 January 2018

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Contractile properties and susceptibility to exercise-induced damage of normal and mdx mouse tibialis anterior muscle

21 January 2018

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Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy

21 January 2018

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Neuronal nitric-oxide synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle

21 January 2018

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Caveolins, liquid-ordered domains, and signal transduction

21 January 2018

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Muscular dystrophies and the dystrophin-glycoprotein complex

21 January 2018

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Molecular pathogenesis of muscle degeneration in the delta-sarcoglycan-deficient hamster

21 January 2018

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Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle

21 January 2018

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Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice

21 January 2018

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Proteolysis results in altered leak channel kinetics and elevated free calcium in mdx muscle.

21 January 2018

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Sparing of mdx extraocular muscles from dystrophic pathology is not attributable to normalized concentration or distribution of neuronal nitric oxide synthase

21 January 2018

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Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species

21 January 2018

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The susceptibility of muscle cells to oxidative stress is independent of nitric oxide synthase expression.

21 January 2018

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Time course of changes in plasma membrane permeability in the dystrophin-deficient mdx mouse

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JEMT.1172

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2 August 2017

1 reference

PubMed ID

11748861