Histone deacetylase inhibitors: discovery and development as anticancer agents (Q34470150)

2 August 2017

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title

Histone deacetylase inhibitors: discovery and development as anticancer agents (English)

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2 August 2017

Paul A Marks

1

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2 August 2017

Milos Dokmanovic

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 December 2005

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Expert Opinion on Investigational Drugs

2 August 2017

published in

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2 August 2017

volume

14

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2 August 2017

issue

12

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2 August 2017

page(s)

1497-1511

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Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylases and cancer: causes and therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Binary switches and modification cassettes in histone biology and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

An increasingly complex code

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Controlling the double helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

The nucleosome: from genomic organization to genomic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone and chromatin cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

The Sir2 family of protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Clinical development of histone deacetylase inhibitors as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Acetylation of proteins as novel target for antitumor therapy: review article.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Regulation of histone deacetylase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Cloning and characterization of a histone deacetylase, HDAC9

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Class II histone deacetylases: versatile regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Cloning and characterization of the murine histone deacetylase (HDAC3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Three proteins define a class of human histone deacetylases related to yeast Hda1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Isolation and characterization of mammalian HDAC10, a novel histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Chicken histone deacetylase-2 controls the amount of the IgM H-chain at the steps of both transcription of its gene and alternative processing of its pre-mRNA in the DT40 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Role of Class I and Class II histone deacetylases in carcinoma cells using siRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

N-terminal region, C-terminal region, nuclear export signal, and deacetylation activity of histone deacetylase-3 are essential for the viability of the DT40 chicken B cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Caspase-mediated specific cleavage of human histone deacetylase 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylase inhibitors in clinical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Expression profile of histone deacetylase 1 in gastric cancer tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Antibody response to a non-conserved C-terminal part of human histone deacetylase 3 in colon cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

HDAC6 expression is correlated with better survival in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Prediction of prognosis of estrogen receptor-positive breast cancer with combination of selected estrogen-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone Deacetylase Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone Deacetylase Inhibitors: The Abbott Experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylase inhibitors: understanding a new wave of anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Deacetylase activity is required for recruitment of the basal transcription machinery and transactivation by STAT5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone acetylation-mediated regulation of genes in leukaemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Specific and redundant functions of histone deacetylases in regulation of cell cycle and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Histone deacetylase inhibitors specifically kill nonproliferating tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

The role of the redox protein thioredoxin in cell growth and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Antioxidant function of thioredoxin and glutaredoxin systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Physiological functions of thioredoxin and thioredoxin reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Cotreatment with histone deacetylase inhibitor LAQ824 enhances Apo-2L/tumor necrosis factor-related apoptosis inducing ligand-induced death inducing signaling complex activity and apoptosis of human acute leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Biology of chronic myeloid leukemia and possible therapeutic approaches to imatinib-resistant disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

FR901228, an inhibitor of histone deacetylases, increases the cellular responsiveness to IL-6 type cytokines by enhancing the expression of receptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Drug insight: Histone deacetylase inhibitors--development of the new targeted anticancer agent suberoylanilide hydroxamic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

Prospects: histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.12.1497

10.1517/13543784.14.12.1497

21 January 2018

Identifiers

DOI

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2 August 2017

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