Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next? (Q34470236)

2 August 2017

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title

Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next? (English)

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2 August 2017

Plasmodium falciparum

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pyrimethamine

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author name string

Sibley CH

1

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2 August 2017

Hyde JE

2

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2 August 2017

Sims PF

3

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2 August 2017

Plowe CV

4

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2 August 2017

Kublin JG

5

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2 August 2017

Mberu EK

6

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2 August 2017

Cowman AF

7

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2 August 2017

Winstanley PA

8

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2 August 2017

Watkins WM

9

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2 August 2017

Nzila AM

10

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2 August 2017

1 December 2001

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2 August 2017

Trends in Parasitology

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2 August 2017

17

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2 August 2017

12

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2 August 2017

582-588

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Chloroquine in Africa: critical assessment and recommendations for monitoring and evaluating chloroquine therapy efficacy in sub-Saharan Africa

2 August 2017

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In vivo selection for a specific genotype of dihydropteroate synthetase of Plasmodium falciparum by pyrimethamine-sulfadoxine but not chlorproguanil-dapsone treatment

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Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites

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Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum

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Kenyan Plasmodium falciparum field isolates: correlation between pyrimethamine and chlorcycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain.

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Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum

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Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins

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Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum

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7 January 2021

Antifolate resistance due to new and known Plasmodium falciparum dihydrofolate reductase mutations expressed in yeast.

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7 January 2021

Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria

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7 January 2021

Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization

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Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum

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A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance.

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In vitro activities of and mechanisms of resistance to antifol antimalarial drugs

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Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria

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7 January 2021

Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance

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7 January 2021

Chlorproguanil/dapsone for uncomplicated Plasmodium falciparum malaria in young children: pharmacokinetics and therapeutic range

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7 January 2021

Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria.

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7 January 2021

Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania

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Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance

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7 January 2021

Molecular basis of in vivo resistance to sulfadoxine-pyrimethamine in African adult patients infected with Plasmodium falciparum malaria parasites.

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Drug resistance in Pneumocystis carinii: an emerging problem

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Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy

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In vitro susceptibility of Plasmodium falciparum malaria to pyrimethamine, sulfadoxine, trimethoprim and sulfamethoxazole, singly and in combination.

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7 January 2021

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Pyrimethamine-sulfadoxine efficacy and selection for mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase in Mali

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Identifiers

DOI

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2 August 2017

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