SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria (Q34470786)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria (English)

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10 March 2020

6

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10 March 2020

author name string

Yukihiro Chino

1

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10 March 2020

Yoshishige Samukawa

2

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10 March 2020

Soichi Sakai

3

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10 March 2020

Yasuhiro Nakai

4

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10 March 2020

Jun-ichi Yamaguchi

5

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10 March 2020

Ikumi Tamai

7

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10 March 2020

publication date

6 August 2014

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Biopharmaceutics and Drug Disposition

10 March 2020

published in

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10 March 2020

volume

35

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10 March 2020

page(s)

391-404

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10 March 2020

issue

7

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Safety, pharmacokinetics, and pharmacodynamics of single and multiple luseogliflozin dosing in healthy Japanese males: a randomized, single-blind, placebo-controlled trial.

10 March 2020

cites work

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Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses

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6 July 2018

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TS-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycaemic activity

6 July 2018

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Elevated serum uric acid concentrations independently predict cardiovascular mortality in type 2 diabetic patients

6 July 2018

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Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

6 July 2018

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Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)

6 July 2018

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SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

6 July 2018

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The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts

6 July 2018

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Human renal organic anion transporter 4 operates as an asymmetric urate transporter

6 July 2018

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The association between serum uric acid level and long-term incidence of hypertension: Population-based cohort study

6 July 2018

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c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney

6 July 2018

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6 July 2018

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Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The interaction between uric acid level and other risk factors on the development of gout among asymptomatic hyperuricemic men in a prospective study.

21 January 2018

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Prevalence of the metabolic syndrome in individuals with hyperuricemia

27 October 2018

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12 December 2020

Uric acid and diabetes: observations in a population study

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12 December 2020

Diabetes, prediabetes and uricaemia

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12 December 2020

Uric acid as an independent risk factor in the treatment of hypertension

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12 December 2020

Effect of phloridzin on uric acid excretion in man

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12 December 2020

Renal metabolism of uric acid in type I insulin-dependent diabetic patients: relation to metabolic compensation

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12 December 2020

The metabolism of uric acid in the normal and gouty human studied with the aid of isotopic uric acid

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12 December 2020

Serum uric acid and cardiovascular events in successfully treated hypertensive patients

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12 December 2020

Identifiers

DOI

10.1002/BDD.1909

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25044127%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

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