Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacology (Q34472770)

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English	Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacology	scientific article

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacology (English)

1 reference

Europe PubMed Central

2 August 2017

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1 reference

based on heuristic

inferred from title

author name string

Jennifer L Whistler

1

1 reference

Europe PubMed Central

2 August 2017

publication date

9 January 2012

1 reference

Europe PubMed Central

2 August 2017

Drug and Alcohol Dependence

1 reference

Europe PubMed Central

2 August 2017

121

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Europe PubMed Central

2 August 2017

3

1 reference

Europe PubMed Central

2 August 2017

189-204

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Europe PubMed Central

2 August 2017

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The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.

1 reference

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1 reference

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6 July 2018

micro-Opioid receptor endocytosis prevents adaptations in ventral tegmental area GABA transmission induced during naloxone-precipitated morphine withdrawal

1 reference

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Biomarkers of morphine tolerance and dependence are prevented by morphine-induced endocytosis of a mutant mu-opioid receptor

1 reference

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Functional characterization of human variants of the mu-opioid receptor gene

1 reference

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6 July 2018

Self administration of heroin and cocaine in morphine-dependent and morphine-withdrawn rhesus monkeys

1 reference

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6 July 2018

Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain

1 reference

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Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence

1 reference

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When it comes to opiates, just say NO.

1 reference

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Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests

1 reference

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6 July 2018

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

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6 July 2018

Expression of spinal NMDA receptor and PKCgamma after chronic morphine is regulated by spinal glucocorticoid receptor.

1 reference

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Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons

1 reference

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6 July 2018

Receptor endocytosis counteracts the development of opioid tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Brain substrates for increased drug seeking during protracted withdrawal

1 reference

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6 July 2018

Drugs used in the treatment of opioid tolerance and physical dependence: a review.

1 reference

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6 July 2018

Historical review: Molecular and cellular mechanisms of opiate and cocaine addiction

1 reference

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Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Cellular and synaptic adaptations mediating opioid dependence.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Are NMDA receptors involved in opiate-induced neural and behavioral plasticity? A review of preclinical studies

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6 July 2018

Methadone: a review of its pharmacokinetic/pharmacodynamic properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Dissociation of functional roles of dynamin in receptor-mediated endocytosis and mitogenic signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

G-protein-coupled receptor heterodimerization modulates receptor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

d-Methadone blocks morphine tolerance and N-methyl-D-aspartate-induced hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Morphine-activated opioid receptors elude desensitization by beta-arrestin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

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G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

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Dopamine-dependent responses to morphine depend on glucocorticoid receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Agonist-selective endocytosis of mu opioid receptor by neurons in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Morphine activates opioid receptors without causing their rapid internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Desensitization of G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Localization of d- and l-methadone after intraventricular injection into rat brains

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6 July 2018

Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Neural mechanisms of drug reinforcement

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Opioids excite dopamine neurons by hyperpolarization of local interneurons.

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6 July 2018

Two types of neurone in the rat ventral tegmental area and their synaptic inputs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

6 July 2018

Morphine-induced mu opioid receptor trafficking enhances reward yet prevents compulsive drug use.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

27 October 2018

Pharmacologic comparison of the optical isomers of methadon.

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27 October 2018

An opiate cocktail that reduces morphine tolerance and dependence

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

27 October 2018

Spinal glucocorticoid receptors contribute to the development of morphine tolerance in rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4224378

27 October 2018

Drug seeking becomes compulsive after prolonged cocaine self-administration.

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27 October 2018

Stress enables synaptic depression in CA1 synapses by acute and chronic morphine: possible mechanisms for corticosterone on opiate addiction.

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27 October 2018

Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal

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27 October 2018

Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons.

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27 October 2018

The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance

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27 October 2018

Opioid tolerance: the clinical perspective

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27 October 2018

The d- and l-isomers of methadone bind to the non-competitive site on the N-methyl-D-aspartate (NMDA) receptor in rat forebrain and spinal cord.

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27 October 2018

The mu1, mu2, delta, kappa opioid receptor binding profiles of methadone stereoisomers and morphine

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27 October 2018

Molecular mechanisms of drug addiction

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https://pubmed.ncbi.nlm.nih.gov/22226706

12 December 2020

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Relapse rates in addiction programs

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https://pubmed.ncbi.nlm.nih.gov/22226706

12 December 2020

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Ketobemidone, methadone and pethidine are non-competitive N-methyl-D-aspartate (NMDA) antagonists in the rat cortex and spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/22226706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased probability of GABA release during withdrawal from morphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22226706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of G protein-coupled receptor desensitization and resensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22226706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.DRUGALCDEP.2011.10.031

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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