Alcoholic liver injury: pathogenesis and therapy in 2001. (Q34473986)

2 August 2017

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title

Alcoholic liver injury: pathogenesis and therapy in 2001. (English)

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2 August 2017

Lieber CS

1

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2 August 2017

1 November 2001

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2 August 2017

Pathology and Biology

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2 August 2017

49

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2 August 2017

9

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2 August 2017

738-752

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EFFECTS OF PROLONGED ETHANOL INTAKE: PRODUCTION OF FATTY LIVER DESPITE ADEQUATE DIETS.

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Perivenular fibrosis as precursor lesion of cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Attenuation of alcohol-induced hepatic fibrosis by polyunsaturated lecithin

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Lipocytes and transitional cells in alcoholic liver disease: A morphometric study

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

The evolution of human cirrhosis deduced from observations in experimental animals

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Alterations in endothelial fenestrations in liver sinusoids of baboons fed alcohol: a scanning electron microscopic study

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Naltrexone and coping skills therapy for alcohol dependence. A controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Combined efficacy of acamprosate and disulfiram in the treatment of alcoholism: a controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

An experimental model of alcohol feeding and liver injury in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Regulation by hypoxia of methionine adenosyltransferase activity and gene expression in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Chronic ethanol consumption alters rat liver plasma membranes and potentiates release of alkaline phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Reversal of intrahepatic cholestasis of pregnancy in women after high dose S-adenosyl-L-methionine administration

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial.

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Hepatic Phosphatidylethanolamine Methyltransferase Activity Is Decreased by Ethanol and Increased by Phosphatidylcholine

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Dietary linoleic acid is required for development of experimentally induced alcoholic liver injury

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Increased type I procollagen mRNA levels and in vitro protein synthesis in the baboon model of chronic alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Dilinoleoylphosphatidylcholine decreases hepatic stellate cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Biochemical and morphological alterations of baboon hepatic mitochondria after chronic ethanol consumption

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Decreased cytochrome oxidase activity in hepatic mitochondria after chronic ethanol consumption and the possible role of decreased cytochrome aa3 content and changes in phospholipids

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Polyenylphosphatidylcholine attenuates alcohol-induced fatty liver and hyperlipemia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Polyenylphosphatidylcholine attenuates non-alcoholic hepatic fibrosis and accelerates its regression.

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Polyunsaturated lecithin prevents acetaldehyde-mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Alcohol, vitamin A, and beta-carotene: adverse interactions, including hepatotoxicity and carcinogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Hepatic vitamin A depletion in alcoholic liver injury

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Hepatic vitamin A depletion after chronic ethanol consumption in baboons and rats

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Changes in vitamin A status after acute ethanol administration in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Increased metabolism of retinoic acid after chronic ethanol consumption in rat liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Decreased hepatic vitamin A after drug administration in men and in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Potentiation of ethanol-induced hepatic vitamin A depletion by phenobarbital and butylated hydroxytoluene

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Retinoic acid metabolism by a system reconstituted with cytochrome P-450

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

NAD+-dependent retinol dehydrogenase in liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8

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https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Interaction of drugs and retinol.

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Chronic alcohol intake reduces retinoic acid concentration and enhances AP-1 (c-Jun and c-Fos) expression in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Liver damage caused by therapeutic vitamin A administration: estimate of dose-related toxicity in 41 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Vitamin A treatment of sexual dysfunction in male alcoholics

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Hepatic fibrosis after long-term administration of ethanol and moderate vitamin A supplementation in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Interactions between alcohol and beta-carotene in patients with alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Interaction of ethanol with beta-carotene: delayed blood clearance and enhanced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

beta-Carotene beadlets potentiate hepatotoxicity of alcohol

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Oxidative changes associated with beta-carotene and alpha-tocopherol enrichment of human low-density lipoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

The effect of ethanol on fatty acid metabolism; stimulation of hepatic fatty acid synthesis in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Purification and characterization of human liver cytochrome P-450-ALC

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Increase of ethanol, meprobamate and pentobarbital metabolism after chronic ethanol administration in man and in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Reduced nicotinamide-adenine dinucleotide phosphate oxidase: activity enhanced by ethanol consumption

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Induction of cytochrome P-4502E1 by ethanol in rat Kupffer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease. Evidence of lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Hepatic, metabolic, and nutritional disorders of alcoholism: from pathogenesis to therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Difference in Hepatic Metabolism of Long- and Medium-Chain Fatty Acids: the Role of Fatty Acid Chain Length in the Production of the Alcoholic Fatty Liver*

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

A randomized trial of prednisolone in patients with severe alcoholic hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Dilinoleoylphosphatidylcholine selectively modulates lipopolysaccharide-induced Kupffer cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

Oxidative stress, antioxidants, and alcoholic liver fibrogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0369-8114%2801%2900239-5

7 January 2021

10.1016/S0369-8114(01)00239-5

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11762137