Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom (Q34477088)

2 August 2017

Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom (English)

1 reference

2 August 2017

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Quentin Kaas

3

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Sébastien Dutertre

object named as

Sébastien Dutertre

1

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Richard J. Lewis

object named as

Richard J Lewis

6

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author name string

Ai-hua Jin

2

1 reference

2 August 2017

Alun Jones

4

1 reference

2 August 2017

Paul F Alewood

5

1 reference

2 August 2017

language of work or name

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14 November 2012

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Molecular & Cellular Proteomics

2 August 2017

1 reference

2 August 2017

12

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2 August 2017

312-329

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2 August 2017

2

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Molecular phylogeny, classification and evolution of conopeptides

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Towards an integrated venomics approach for accelerated conopeptide discovery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Conus venom peptide pharmacology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Novel venom peptides from the cone snail Conus pulicarius discovered through next-generation sequencing of its venom duct transcriptome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

iAssembler: a package for de novo assembly of Roche-454/Sanger transcriptome sequences

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Discovery and development of the χ-conopeptide class of analgesic peptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Characterization of the Conus bullatus genome and its venom-duct transcriptome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Messy biology and the origins of evolutionary innovations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Chemical synthesis and characterization of two α4/7-conotoxins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Conopeptide characterization and classifications: an analysis using ConoServer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Venomics: a new paradigm for natural products-based drug discovery.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Conotoxin venom peptide therapeutics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Comparative proteomic study of the venom of the piscivorous cone snail Conus consors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Purification and structural characterization of a D-amino acid-containing conopeptide, conomarphin, from Conus marmoreus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Structure and Sodium Channel Activity of an Excitatory I 1 -Superfamily Conotoxin † , ‡

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Sequence diversity of O-superfamily conopetides from Conus marmoreus native to Hainan

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Venom landscapes: mining the complexity of spider venoms via a combined cDNA and mass spectrometric approach

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Conotoxins and the posttranslational modification of secreted gene products

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Precursors of novel Gla-containing conotoxins contain a carboxy-terminal recognition site that directs gamma-carboxylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Polypeptide chains containing D-gamma-hydroxyvaline

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Species-level phylogeography and evolutionary history of the hyperdiverse marine gastropod genus Conus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Ziconotide: neuronal calcium channel blocker for treating severe chronic pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

The first gamma-carboxyglutamic acid-containing contryphan. A selective L-type calcium ion channel blocker isolated from the venom of Conus marmoreus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

The Jalview Java alignment editor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Therapeutic potential of venom peptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Cone venom--from accidental stings to deliberate injection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

lambda-conotoxins, a new family of conotoxins with unique disulfide pattern and protein folding. Isolation and characterization from the venom of Conus marmoreus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Isolation and characterization of a novel conus peptide with apparent antinociceptive activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Molecular genetics of ecological diversification: duplication and rapid evolution of toxin genes of the venomous gastropod Conus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Solution structure of omega-conotoxin GVIA using 2-D NMR spectroscopy and relaxation matrix analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

A new family of Conus peptides targeted to the nicotinic acetylcholine receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

A new family of conotoxins that blocks voltage-gated sodium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Peptide neurotoxins from fish-hunting cone snails

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Multiple sequence alignment with hierarchical clustering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

Constant and hypervariable regions in conotoxin propeptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3567856

The projectile tooth of a fish-hunting cone snail: Conus catus injects venom into fish prey using a high-speed ballistic mechanism

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

High-resolution picture of a venom gland transcriptome: case study with the marine snail Conus consors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

A novel post-translational modification involving bromination of tryptophan. Identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venom

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Mechanisms for evolving hypervariability: the case of conopeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Specialisation of the Venom Gland Proteome in Predatory Cone Snails Reveals Functional Diversification of the Conotoxin Biosynthetic Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Analgesic alpha-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

TxXIIIA, an atypical homodimeric conotoxin found in the Conus textile venom.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Isolation and characterization of three novel Gla-containing Conus marmoreus venom peptides, one with a novel cysteine pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Two different groups of signal sequence in M-superfamily conotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Novel conopeptides in a form of disulfide-crosslinked dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Two short D-Phe-containing cysteine-free conopeptides from Conus marmoreus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Gene expression and feeding ecology: evolution of piscivory in the venomous gastropod genus Conus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Evolutionary diversification of multigene families: allelic selection of toxins in predatory cone snails.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Two potent alpha3/5 conotoxins from piscivorous Conus achatinus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M112.021469

The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors

21 January 2018

1 reference

12 December 2020

The venom apparatus of Conus magus

1 reference

12 December 2020

New sodium channel-blocking conotoxins also affect calcium currents in Lymnaea neurons

1 reference

12 December 2020

Sequence diversity of T-superfamily conotoxins from Conus marmoreus

1 reference

12 December 2020

Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms

1 reference

12 December 2020

Characterization of novel M-superfamily conotoxins with new disulfide linkage

1 reference

12 December 2020

ConoServer, a database for conopeptide sequences and structures

1 reference

12 December 2020

mr1e, a conotoxin from Conus marmoreus with a novel disulfide pattern

1 reference

12 December 2020

Remarkable inter- and intra-species complexity of conotoxins revealed by LC/MS

1 reference

12 December 2020

Venom kinematics during prey capture in Conus: the biomechanics of a rapid injection system

1 reference

12 December 2020

Identifiers

DOI

10.1074/MCP.M112.021469

1 reference

2 August 2017

1 reference

2 August 2017

1 reference