Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells (Q34478047)

2 August 2017

Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells (English)

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2 August 2017

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B Vogelstein

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2 August 2017

3

K W Kinzler

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2 August 2017

B H Park

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PubMed ID

11226285

2 August 2017

language of work or name

English

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publication date

1 February 2001

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Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

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2 August 2017

98

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2 August 2017

5

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2 August 2017

2598-2603

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PubMed ID

11226285

describes a project that uses

2 August 2017

HCT 116 PPARD(-/-)

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cites work

Surfing the p53 network

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Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer

6 July 2018

1 reference

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Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

6 July 2018

1 reference

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Roles of PPARs in health and disease.

6 July 2018

1 reference

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Peroxisome proliferator-activated receptors: insight into multiple cellular functions

6 July 2018

1 reference

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PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Activators of the nuclear receptor PPARgamma enhance colon polyp formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Identification of c-MYC as a target of the APC pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

A simplified system for generating recombinant adenoviruses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis

6 July 2018

1 reference

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Improved dicistronic mRNA expression vectors for efficient selection of transfectants highly expressing foreign genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=30184

Frequent activation of the beta-catenin-Tcf signaling pathway in nonfamilial colorectal carcinomas with microsatellite instability

6 July 2018

1 reference

12 December 2020

Manipulation of transgenes by site-specific recombination: use of Cre recombinase

1 reference

12 December 2020

Differentiation and reversal of malignant changes in colon cancer through PPARgamma

1 reference

12 December 2020

Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.051630998

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2 August 2017

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1 reference

2 August 2017

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PubMed ID

11226285