Keynote review: histamine H3 receptor antagonists reach out for the clinic (Q34479438)

2 August 2017

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title

Keynote review: histamine H3 receptor antagonists reach out for the clinic (English)

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2 August 2017

2

Maikel Wijtmans

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2 August 2017

Sylvain Celanire

1

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2 August 2017

Patrice Talaga

series ordinal

3

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2 August 2017

Rob Leurs

series ordinal

4

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2 August 2017

Iwan J P de Esch

series ordinal

5

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2 August 2017

publication date

1 December 2005

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2 August 2017

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2 August 2017

volume

10

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2 August 2017

issue

23-24

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2 August 2017

page(s)

1613-1627

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Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Highly potent and selective ligands for histamine H3-receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Three histamine receptors (H1, H2 and H3) visualized in the brain of human and non-human primates.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

The role of histamine and the tuberomamillary nucleus in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Cloning and functional expression of the human histamine H3 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Molecular cloning and characterization of a new human histamine receptor, HH4R

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Molecular and pharmacological characterization of the mouse histamine H3 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Cloning and cerebral expression of the guinea pig histamine H3 receptor: evidence for two isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Histamine H3-receptor isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

The histamine H3 receptor: from gene cloning to H3 receptor drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Protean agonism at histamine H3 receptors in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

G protein-dependent pharmacology of histamine H3 receptor ligands: evidence for heterogeneous active state receptor conformations

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

The histamine H3 receptor as a novel therapeutic target for cognitive and sleep disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Perspectives on cognitive domains, H3 receptor ligands and neurological disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Involvement of histamine in the control of the waking state

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Selective histamine H3 receptor antagonists for treatment of cognitive deficiencies and other disorders of the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Effects of histamine H3 receptor antagonists in two models of spatial learning

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Histamine H3 ligands: just pharmacological tools or potential therapeutic agents?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Effects of clobenpropit (VUF-9153), a histamine H3-receptor antagonist, on learning and memory, and on cholinergic and monoaminergic systems in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Two novel and selective nonimidazole H3 receptor antagonists A-304121 and A-317920: II. In vivo behavioral and neurophysiological characterization

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Hypothalamic neuronal histamine as a target of leptin in feeding behavior

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Histamine and selective H3-receptor ligands: a possible role in the mechanism and management of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Neuropharmacology of the histaminergic neuron system in the brain and its relationship with behavioral disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

The role of the central histaminergic system on schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Rodent antinociception following acute treatment with different histamine receptor agonists and antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, modulates the effects of methamphetamine on neuropeptide mRNA expression in rat striatum

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Histamine-mediated mechanisms in the human nasal airway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Pharmacological characterization of the novel histamine H3-receptor antagonist N-(3,5-dichlorophenyl)-N'-[[4-(1H-imidazol-4-ylmethyl)phenyl]-methyl]-urea (SCH 79687).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

H3 receptor ligands: new imidazole H3-antagonists endowed with NO-donor properties

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H(3) receptor agonist

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

The first potent and selective non-imidazole human histamine H4 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Inhibition and induction of cytochrome P450 and the clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, potentiates neurochemical and behavioral effects of haloperidol in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Synthesis of potent non-imidazole histamine H3-receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Influence of imidazole replacement in different structural classes of histamine H(3)-receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Search for histamine H(3) receptor ligands with combined inhibitory potency at histamine N-methyltransferase: omega-piperidinoalkanamine derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Design, synthesis, and structure-activity relationships of novel non-imidazole histamine H(3) receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Design, synthesis, and structure-activity relationships of acetylene-based histamine H3 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Characteristics of recombinantly expressed rat and human histamine H3 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

An efficient multigram synthesis of the potent histamine H3 antagonist GT-2331 and the reassessment of the absolute configuration

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Combined histamine H1 and H3 receptor blockade produces nasal decongestion in an experimental model of nasal congestion

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Effect of combined histamine H1 and H3 receptor blockade on cutaneous microvascular permeability elicited by compound 48/80.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Identification of a novel, orally bioavailable histamine H(3) receptor antagonist based on the 4-benzyl-(1H-imidazol-4-yl) template

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 3: 5-Substituted 3-phenyl-1,2,4-oxadiazoles as potent antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 2: binding preference for D-amino acids motifs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

D-amino acid homopiperazine amides: discovery of A-320436, a potent and selective non-imidazole histamine H(3)-receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Synthesis and SAR of aminoalkoxy-biaryl-4-carboxamides: novel and selective histamine H3 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Aminoalkoxybiphenylnitriles as histamine-3 receptor ligands

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

In vitro optimization of structure activity relationships of analogues of A-331440 combining radioligand receptor binding assays and micronucleus assays of potential antiobesity histamine H3 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Assessment of pharmacology and potential anti-obesity properties of H3 receptor antagonists/inverse agonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

A new class of potent non-imidazole H(3) antagonists: 2-aminoethylbenzofurans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

1 reference

7 January 2021

Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Structure-activity relationships of arylbenzofuran H3 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Novel human histamine H(3) receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Non-imidazole heterocyclic histamine H3 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

A new class of diamine-based human histamine H3 receptor antagonists: 4-(aminoalkoxy)benzylamines

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Acute wake-promoting actions of JNJ-5207852, a novel, diamine-based H3 antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

4-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

A scalable synthesis of a histamine H3 receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

1-alkyl-4-acylpiperazines as a new class of imidazole-free histamine H(3) receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Non-imidazole histamine H3 ligands, Part 2: New 2-substituted benzothiazoles as histamine H3 antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

2-(4-alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

Cinnamic amides of (S)-2-(aminomethyl)pyrrolidines are potent H3 antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903625-1

7 January 2021

10.1016/S1359-6446(05)03625-1

Identifiers

DOI

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2 August 2017

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