Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin (Q34483577)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452635%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin (English)

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16 January 2020

1

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16 January 2020

Diana Zala

3

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16 January 2020

Frédéric Saudou

7

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16 January 2020

Etienne C. Hirsch

9

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16 January 2020

Nicole Déglon

11

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16 January 2020

Emmanuel Brouillet

12

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16 January 2020

10

Philippe Hantraye

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16 January 2020

2

Yaël Trioulier

1 reference

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16 January 2020

Marie-Claude Gaillard

4

object named as

Marie-Claude Gaillard

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16 January 2020

8

Jean-Marc Elalouf

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16 January 2020

author name string

Nathalie Lefort

5

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16 January 2020

Noelle Dufour

6

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16 January 2020

publication date

1 February 2006

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Molecular Biology of the Cell

16 January 2020

published in

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16 January 2020

volume

17

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16 January 2020

issue

4

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16 January 2020

page(s)

1652-1663

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3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease.

16 January 2020

cites work

1 reference

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PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

6 July 2018

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Role of molecular chaperones in neurodegenerative disorders

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p53 in neuronal apoptosis

6 July 2018

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Identification of a putative p53 binding sequence within the human mitochondrial genome

6 July 2018

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Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues

6 July 2018

1 reference

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Huntingtin and its role in neuronal degeneration

6 July 2018

1 reference

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Deranged neuronal calcium signaling and Huntington disease.

6 July 2018

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

6 July 2018

1 reference

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Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway

6 July 2018

1 reference

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Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

6 July 2018

1 reference

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Transcriptional abnormalities in Huntington disease

6 July 2018

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Comparison of the effect of mitochondrial inhibitors on mitochondrial membrane potential in two different cell lines using flow cytometry and spectrofluorometry.

6 July 2018

1 reference

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Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

6 July 2018

1 reference

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Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

6 July 2018

1 reference

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Succinate dehydrogenase and human diseases: new insights into a well-known enzyme

6 July 2018

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Active caspase-8 translocates into the nucleus of apoptotic cells to inactivate poly(ADP-ribose) polymerase-2

6 July 2018

1 reference

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Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length.

6 July 2018

1 reference

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Metabolic changes in the basal ganglia of patients with Huntington's disease: an in situ hybridization study of cytochrome oxidase subunit I mRNA.

6 July 2018

1 reference

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Does tissue transglutaminase play a role in Huntington's disease?

6 July 2018

1 reference

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The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

6 July 2018

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Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

6 July 2018

1 reference

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Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

6 July 2018

1 reference

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Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles

6 July 2018

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Progress in understanding structure-function relationships in respiratory chain complex II.

6 July 2018

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Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

6 July 2018

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Replicating Huntington's disease phenotype in experimental animals

6 July 2018

1 reference

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Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

6 July 2018

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Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements

6 July 2018

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

6 July 2018

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Assay of succinate dehydrogenase activity by a colorimetric-continuous method using iodonitrotetrazolium chloride as electron acceptor.

6 July 2018

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Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome

6 July 2018

1 reference

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Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency

6 July 2018

1 reference

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Regional mitochondrial respiratory activity in Huntington's disease brain

6 July 2018

1 reference

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Neuropathological classification of Huntington's disease

6 July 2018

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Distribution of phosphate-activated glutaminase, succinic dehydrogenase, pyruvate dehydrogenase and gamma-glutamyl transpeptidase in post-mortem brain from Huntington's disease and agonal cases

6 July 2018

1 reference

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

6 July 2018

1 reference

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Mitochondrial function and parental sex effect in Huntington's disease

6 July 2018

1 reference

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Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

6 July 2018

1 reference

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

6 July 2018

1 reference

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Progressive and selective striatal degeneration in primary neuronal cultures using lentiviral vector coding for a mutant huntingtin fragment

6 July 2018

1 reference

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p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

27 October 2018

1 reference

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Early and reversible neuropathology induced by tetracycline-regulated lentiviral overexpression of mutant huntingtin in rat striatum

27 October 2018

1 reference

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Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease.

27 October 2018

1 reference

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Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease.

27 October 2018

1 reference

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Specific caspase pathways are activated in the two stages of cerebral infarction.

27 October 2018

1 reference

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Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy

27 October 2018

1 reference

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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

27 October 2018

1 reference

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Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

27 October 2018

1 reference

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415305

Trinucleotide (CAG) repeat length is positively correlated with the degree of DNA fragmentation in Huntington's disease striatum

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415305

1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers

27 October 2018

1 reference

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Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415305

Mitochondrial defect in Huntington's disease caudate nucleus

27 October 2018

1 reference

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Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

27 October 2018

1 reference

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DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415305

Compound heterozygous mutations in the flavoprotein gene of the respiratory chain complex II in a patient with Leigh syndrome

27 October 2018

1 reference

12 December 2020

The use of chloromethyl-X-rosamine (Mitotracker red) to measure loss of mitochondrial membrane potential in apoptotic cells is incompatible with cell fixation

1 reference

12 December 2020

Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

1 reference

12 December 2020

Activation of proinflammatory caspases by cathepsin B in focal cerebral ischemia

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E05-07-0607

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452635%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452635%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference