Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis (Q34486069)

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English	Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis	scientific article

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis (English)

1 reference

Europe PubMed Central

2 August 2017

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toll-like receptor

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author name string

Giuseppina Stifano

1

1 reference

Europe PubMed Central

2 August 2017

Alsya J Affandi

2

1 reference

Europe PubMed Central

2 August 2017

Allison L Mathes

3

1 reference

Europe PubMed Central

2 August 2017

Lisa M Rice

4

1 reference

Europe PubMed Central

2 August 2017

Sashidhar Nakerakanti

5

1 reference

Europe PubMed Central

2 August 2017

Banafsheh Nazari

6

1 reference

Europe PubMed Central

2 August 2017

Jungeun Lee

7

1 reference

Europe PubMed Central

2 August 2017

Romy B Christmann

8

1 reference

Europe PubMed Central

2 August 2017

Robert Lafyatis

9

1 reference

Europe PubMed Central

2 August 2017

publication date

1 July 2014

1 reference

Europe PubMed Central

2 August 2017

Arthritis Research and Therapy

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Europe PubMed Central

2 August 2017

16

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Europe PubMed Central

2 August 2017

4

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Europe PubMed Central

2 August 2017

R136

1 reference

Europe PubMed Central

2 August 2017

https://scigraph.springernature.com/pub.10.1186/ar4598

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Thymic stromal lymphopoietin is up-regulated in the skin of patients with systemic sclerosis and induces profibrotic genes and intracellular signaling that overlap with those induced by interleukin-13 and transforming growth factor β.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

The role of chronic inflammation in cutaneous fibrosis: fibroblast growth factor receptor deficiency in keratinocytes as an example

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Protective and pathogenic functions of macrophage subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Toll-like receptor signaling and liver fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Skin thickness progression rate: a predictor of mortality and early internal organ involvement in diffuse scleroderma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Macrophages: master regulators of inflammation and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

A four-gene biomarker predicts skin disease in patients with diffuse cutaneous systemic sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Toll-like receptor 4: a novel signaling pathway during renal fibrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Recombinant human relaxin in the treatment of systemic sclerosis with diffuse cutaneous involvement: a randomized, double-blind, placebo-controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

TLR accessory molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

LPS/TLR4 signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

TLR4 enhances TGF-beta signaling and hepatic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Pathogen recognition and innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

New insights into the molecular mechanism of interleukin-10-mediated immunosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Molecular mechanisms of endotoxin tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Bacterial lipopolysaccharides and innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Soluble CD14 participates in the response of cells to lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

6 July 2018

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

27 October 2018

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

27 October 2018

Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

27 October 2018

Evaluation of interleukin 13 polymorphisms in systemic sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

27 October 2018

CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

27 October 2018

The modified Rodnan skin score is an accurate reflection of skin biopsy thickness in systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

27 October 2018

Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227089

27 October 2018

Updating the American College of Rheumatology preliminary classification criteria for systemic sclerosis: addition of severe nailfold capillaroscopy abnormalities markedly increases the sensitivity for limited scleroderma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24984848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scleroderma (systemic sclerosis): classification, subsets and pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24984848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24984848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and toll-like receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/24984848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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