Direct three-dimensional visualization of membrane disruption by amyloid fibrils (Q34489472)

2 August 2017

Direct three-dimensional visualization of membrane disruption by amyloid fibrils (English)

1 reference

2 August 2017

1 reference

8

1 reference

2 August 2017

Wei-Feng Xue

3

0 references

Elena V. Orlova

Elena V Orlova

4

0 references

Andrew L Hellewell

Andrew L Hellewell

5

0 references

Raz Jelinek

Raz Jelinek

6

0 references

Eric W Hewitt

Eric W Hewitt

7

0 references

Helen Saibil

9

Helen R Saibil

1 reference

2 August 2017

Lilia Milanesi

1

1 reference

PubMed ID

23184970

2 August 2017

Tania Sheynis

2

1 reference

PubMed ID

23184970

2 August 2017

language of work or name

English

0 references

publication date

26 November 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

1 reference

2 August 2017

109

1 reference

2 August 2017

20455-20460

1 reference

2 August 2017

50

1 reference

Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Direct observation of the interconversion of normal and toxic forms of α-synuclein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Membrane fission is promoted by insertion of amphipathic helices and is restricted by crescent BAR domains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

A molecular history of the amyloidoses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Characterization of the response of primary cells relevant to dialysis-related amyloidosis to β2-microglobulin monomer and fibrils

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Single-channel Ca(2+) imaging implicates Aβ1-42 amyloid pores in Alzheimer's disease pathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Molecular basis for amyloid- polymorphism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Molecular chaperones in protein folding and proteostasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

A diversity of assembly mechanisms of a generic amyloid fold

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

In vivo demonstration that alpha-synuclein oligomers are toxic

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Intermolecular alignment in β2-microglobulin amyloid fibrils

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Molecular pathology of human prion disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

The non-core regions of human lysozyme amyloid fibrils influence cytotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Amyloidogenic protein-membrane interactions: mechanistic insight from model systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Prion induction involves an ancient system for the sequestration of aggregated proteins and heritable changes in prion fragmentation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Stacked sets of parallel, in-register beta-strands of beta2-microglobulin in amyloid fibrils revealed by site-directed spin labeling and chemical labeling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Architecture of a nascent viral fusion pore

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Kinesin motor activation: microtubules pull the switches

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

A causative link between the structure of aberrant protein oligomers and their toxicity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

An analytical solution to the kinetics of breakable filament assembly

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Fibril fragmentation enhances amyloid cytotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Biological and chemical approaches to diseases of proteostasis deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

A common beta-sheet architecture underlies in vitro and in vivo beta2-microglobulin amyloid fibrils

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

The mechanism of pore formation by bacterial toxins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Membrane curvature and mechanisms of dynamic cell membrane remodelling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Molecular recycling within amyloid fibrils

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Rapid preparation of giant unilamellar vesicles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

Computer visualization of three-dimensional image data using IMOD

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528594

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Mechanism of membrane interaction and disruption by α-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Islet amyloid polypeptide forms rigid lipid-protein amyloid fibrils on supported phospholipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Formation of toxic Abeta(1-40) fibrils on GM1 ganglioside-containing membranes mimicking lipid rafts: polymorphisms in Abeta(1-40) fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

A systematic study of the effect of physiological factors on beta2-microglobulin amyloid formation at neutral pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Effect of lipid type on the binding of lipid vesicles to islet amyloid polypeptide amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Phospholipid catalysis of diabetic amyloid assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Competing pathways determine fibril morphology in the self-assembly of beta2-microglobulin into amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Amyloid Fibrils of Mammalian Prion Protein Are Highly Toxic to Cultured Cells and Primary Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Noise Reduction in Electron Tomographic Reconstructions Using Nonlinear Anisotropic Diffusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206325109

Mutual modulation between membrane-embedded receptor clustering and ligand binding in lipid membranes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23184970

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Surface structure of amyloid-beta fibrils contributes to cytotoxicity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23184970

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1206325109

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference

PubMed ID

23184970