High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses (Q34501474)

2 August 2017

High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses (English)

1 reference

2 August 2017

Joseph J Sabatino

1

1 reference

2 August 2017

Jun Huang

series ordinal

2

1 reference

2 August 2017

Cheng Zhu

series ordinal

3

1 reference

2 August 2017

Brian D Evavold

series ordinal

4

1 reference

2 August 2017

language of work or name

English

0 references

publication date

10 January 2011

1 reference

Journal of Experimental Medicine

2 August 2017

1 reference

2 August 2017

208

1 reference

2 August 2017

1

1 reference

2 August 2017

81-90

1 reference

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Complete but curtailed T-cell response to very low-affinity antigen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Tricks with tetramers: how to get the most from multimeric peptide-MHC.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Class II major histocompatibility complex tetramer staining: progress, problems, and prospects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Precursor frequency, nonlinear proliferation, and functional maturation of virus-specific CD4+ T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Functional avidity directs T-cell fate in autoreactive CD4+ T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

A kinetic basis for T cell receptor repertoire selection during an immune response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Measuring two-dimensional receptor-ligand binding kinetics by micropipette

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Delineation of the minimal encephalitogenic epitope within the immunodominant region of myelin oligodendrocyte glycoprotein: diverse V beta gene usage by T cells recognizing the core epitope encephalitogenic for T cell receptor V beta b and T cell r

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Phenotypic analysis of antigen-specific T lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Presentation of endogenous viral proteins in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and the TAP transporter system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

Analysis of autoreactive CD4 T cells in experimental autoimmune encephalomyelitis after primary and secondary challenge using MHC class II tetramers

7 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4+ T cell response to a rheumatoid arthritis-associated antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Regulation of polyclonal T cell responses by an MHC anchor-substituted variant of myelin oligodendrocyte glycoprotein 35-55.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Low-avidity recognition by CD4+ T cells directed to self-antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

TCR affinity and negative regulation limit autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Mapping and restriction of a dominant viral CD4+ T cell core epitope by both MHC class I and MHC class II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Kinetics of MHC-CD8 interaction at the T cell membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Low avidity recognition of self-antigen by T cells permits escape from central tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Heterogeneity in the clonal T cell response. Implications for models of T cell activation and cytokine phenotype development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20101574

Posttranslational regulation of TCR Valpha allelic exclusion during T cell differentiation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023139

A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells

27 October 2018

1 reference

12 December 2020

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

1 reference

12 December 2020

Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties

1 reference

12 December 2020

Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen

1 reference

12 December 2020

Induction of anergy by antibody blockade of TCR in myelin oligodendrocyte glycoprotein-specific cells

1 reference

12 December 2020

Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

1 reference

12 December 2020

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

1 reference

12 December 2020

Structure-function analysis of the Abm12 beta mutation using site-directed mutagenesis and DNA-mediated gene transfer

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20101574

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference