A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive disease (Q34502522)

2 August 2017

title

A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive disease (English)

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2 August 2017

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Matthew P Wagoner

1

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2 August 2017

Avtar Roopra

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

7 December 2012

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2 August 2017

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2 August 2017

volume

13

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2 August 2017

page(s)

686

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REST is a novel prognostic factor and therapeutic target for medulloblastoma

2 August 2017

cites work

1 reference

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REST controls self-renewal and tumorigenic competence of human glioblastoma cells

7 July 2018

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REST regulates oncogenic properties of glioblastoma stem cells

7 July 2018

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Utility of oncotype DX risk estimates in clinically intermediate risk hormone receptor‐positive, HER2‐normal, grade II, lymph node‐negative breast cancers

7 July 2018

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The transcription factor REST is lost in aggressive breast cancer

7 July 2018

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The role of the PTEN gene in malignant gliomas

7 July 2018

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

7 July 2018

1 reference

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Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation

7 July 2018

1 reference

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Advances in the genetics of glioblastoma: are we reaching critical mass?

7 July 2018

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REST regulates distinct transcriptional networks in embryonic and neural stem cells

7 July 2018

1 reference

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SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation

7 July 2018

1 reference

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Control of chromosome stability by the beta-TrCP-REST-Mad2 axis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

7 July 2018

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Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

7 July 2018

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An essential switch in subunit composition of a chromatin remodeling complex during neural development

7 July 2018

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Genome-wide mapping of in vivo protein-DNA interactions

7 July 2018

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The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways

7 July 2018

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Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

Reciprocal actions of REST and a microRNA promote neuronal identity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

Adenovirus-mediated gene transfer of MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the recruitment of p27Kip1 into cyclin E/CDK2 complexes

7 July 2018

1 reference

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The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2164-13-686

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2164-13-686

p27 modulates cell cycle progression and chemosensitivity in human malignant glioma.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2164-13-686

Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

Genetic pathways to glioblastoma: a population-based study

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

Gene expression profiling of gliomas strongly predicts survival

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

p27Kip1 expression by contact inhibition as a prognostic index of human glioma.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545737

27 October 2018

Identifiers

DOI

10.1186/1471-2164-13-686

1 reference

2 August 2017

1 reference

2 August 2017

1 reference