Signaling networks that link cell proliferation and cell fate (Q34502845)

2 August 2017

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title

Signaling networks that link cell proliferation and cell fate (English)

1 reference

2 August 2017

Rosalie C Sears

1

1 reference

PubMed ID

11805123

2 August 2017

Joseph R Nevins

series ordinal

2

1 reference

PubMed ID

11805123

2 August 2017

language of work or name

English

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publication date

22 January 2002

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Journal of Biological Chemistry

2 August 2017

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2 August 2017

277

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2 August 2017

14

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2 August 2017

11617-11620

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2 August 2017

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Rb function in cell-cycle regulation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

A Restriction Point for Control of Normal Animal Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Ras enhances Myc protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Mechanisms of apoptosis by c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

c-Myc target genes involved in cell growth, apoptosis, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Differential modulation of cyclin gene expression by MYC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Complex transcriptional regulatory mechanisms control expression of the E2F3 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Multiple Ras functions can contribute to mammalian cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Integration of positive and negative growth signals during ras pathway activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

How do small GTPase signal transduction pathways regulate cell cycle entry?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Multiple ras effector pathways contribute to G(1) cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Increasing complexity of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Ras signalling and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Reversible tumorigenesis by MYC in hematopoietic lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

The Rb/E2F pathway and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

MYC oncogenes and human neoplastic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

21 January 2018

Identifiers

DOI

10.1074/JBC.R100063200

1 reference

2 August 2017

1 reference

PubMed ID

11805123