A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene. (Q34505084)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7708729%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

title

A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene (English)

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24 October 2019

3

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24 October 2019

author name string

M Zhu

1

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24 October 2019

J L Rabinowitz

2

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24 October 2019

B J Kobrin

4

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24 October 2019

M D Scharff

5

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24 October 2019

language of work or name

English

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publication date

1 March 1995

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Proceedings of the National Academy of Sciences of the United States of America

24 October 2019

published in

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24 October 2019

volume

92

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24 October 2019

issue

7

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24 October 2019

page(s)

2810-2814

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Mutations of Bacteria from Virus Sensitivity to Virus Resistance

24 October 2019

cites work

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7 July 2018

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Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

7 July 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

7 July 2018

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Somatic generation of hybrid antibody H chain genes in transgenic mice via interchromosomal gene conversion

7 July 2018

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1 Preparation of monoclonal antibodies: Strategies and procedures

7 July 2018

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Somatic mutation in a cultured mouse myeloma cell affects antigen binding

7 July 2018

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Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice

7 July 2018

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Somatic generation of antibody diversity

7 July 2018

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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

7 July 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

7 July 2018

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Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6.

7 July 2018

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Measurements of mutation rates in B lymphocytes.

7 July 2018

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Mutation drift and repertoire shift in the maturation of the immune response

7 July 2018

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The role of the kappa enhancer and its binding factor NF-kappa B in the developmental regulation of kappa gene transcription

7 July 2018

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High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene

7 July 2018

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The role of somatic hypermutation in the generation of antibody diversity

7 July 2018

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Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways

7 July 2018

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Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response

7 July 2018

1 reference

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Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice

7 July 2018

1 reference

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Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

7 July 2018

1 reference

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Modification, optimization and simplification of the spot ELISA technique for the enumeration of cells secreting anti-hapten antibodies.

7 July 2018

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Distribution of mutations around rearranged heavy-chain antibody variable-region genes

7 July 2018

1 reference

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Intraclonal generation of antibody mutants in germinal centres

7 July 2018

1 reference

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Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.

7 July 2018

1 reference

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Instability of immunoglobulin genes in S107 cell line.

7 July 2018

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Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication

7 July 2018

1 reference

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Identification of rare immunoglobulin switch variants using the ELISA spot assay

7 July 2018

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Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

7 July 2018

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Expansion, selection and mutation of antigen-specific B cells in germinal centers

7 July 2018

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Antigen-binding mutants of mouse myeloma cells

7 July 2018

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Generation of heavy chain-loss mutants in a B cell hybrid mediated by syngeneic idiotype-specific spleen cells.

7 July 2018

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Variability in the Lambda Light Chain Sequences of Mouse Antibody

27 October 2018

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Somatic mutations in antibodies expressed by germinal centre B cells early after primary immunization

27 October 2018

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12 December 2020

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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12 December 2020

Somatic cell genetic analysis of myelomas and hybridomas

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12 December 2020

Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer

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12 December 2020

Somatic cell hybridization of mouse myeloma cells

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12 December 2020

Identifiers

DOI

10.1073/PNAS.92.7.2810

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7708729%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

0 references

1 reference

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24 October 2019

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