DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia (Q34508840)

2 August 2017

DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia (English)

1 reference

2 August 2017

0 references

1 reference

Francesco Napolitano

2

0 references

Annabella Di Giorgio

Annabella Di Giorgio

9

0 references

Alessandro Usiello

Alessandro Usiello

13

0 references

Paolo Taurisano

Paolo Taurisano

4

0 references

Alessandro Bertolino

Alessandro Bertolino

14

0 references

Giuseppe Blasi

Giuseppe Blasi

1

0 references

author name string

Gianluca Ursini

3

1 reference

2 August 2017

Raffaella Romano

5

1 reference

2 August 2017

Grazia Caforio

6

1 reference

2 August 2017

Leonardo Fazio

7

1 reference

2 August 2017

Barbara Gelao

8

1 reference

2 August 2017

Luisa Iacovelli

10

1 reference

2 August 2017

Lorenzo Sinibaldi

11

1 reference

2 August 2017

Teresa Popolizio

12

1 reference

2 August 2017

language of work or name

English

0 references

publication date

27 December 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

1 reference

2 August 2017

108

1 reference

2 August 2017

3

1 reference

2 August 2017

1158-1163

1 reference

D1 and D2 dopamine receptor-mediated inhibition of activated normal T cell proliferation is lost in jurkat T leukemic cells

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Genetically determined measures of striatal D2 signaling predict prefrontal activity during working memory performance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Functional variation of the dopamine D2 receptor gene is associated with emotional control as well as brain activity and connectivity during emotion processing in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Role of dopamine in the physiology of T-cells and dendritic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Computational models of schizophrenia and dopamine modulation in the prefrontal cortex.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

The dual-state theory of prefrontal cortex dopamine function with relevance to catechol-o-methyltransferase genotypes and schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

A signaling pathway AKTing up in schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

The Akt-GSK-3 signaling cascade in the actions of dopamine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Detection of functional single-nucleotide polymorphisms that affect apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

The principal features and mechanisms of dopamine modulation in the prefrontal cortex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

The effects of clozapine on the GSK-3-mediated signaling pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Distinct functions of the two isoforms of dopamine D2 receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Increased baseline occupancy of D2 receptors by dopamine in schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Imaging dopamine transmission in schizophrenia. A review and meta-analysis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Dopamine, the prefrontal cortex and schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Neural mechanisms of selective visual attention

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Implications of normal brain development for the pathogenesis of schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Selective D2 receptor actions on the functional circuitry of working memory

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Central D2 receptors and negative symptoms of schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Dopamine D2 receptor occupancy levels of acute sulpiride challenges that produce working memory and learning impairments in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Differentiating allocation of resources and conflict detection within attentional control processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Cognitive impairments in patients with schizophrenia displaying preserved and compromised intellect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Nonlinear response of the anterior cingulate and prefrontal cortex in schizophrenia as a function of variable attentional control

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Mice lacking dopamine D2 and D3 receptors exhibit differential activation of prefrontal cortical neurons during tasks requiring attention

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Frontal and temporal dopamine release during working memory and attention tasks in healthy humans: a positron emission tomography study using the high-affinity dopamine D2 receptor ligand [11C]FLB 457.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Effect of catechol-O-methyltransferase val158met genotype on attentional control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Association analysis of AKT1 and schizophrenia in a UK case control sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

Interaction of COMT (Val(108/158)Met) genotype and olanzapine treatment on prefrontal cortical function in patients with schizophrenia.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024671

COMT Val158Met polymorphism predicts negative symptoms response to treatment with olanzapine in schizophrenia

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013535108

The genetics of schizophrenia

21 January 2018

1 reference

12 December 2020

Processing of context information in schizophrenia: relation to clinical symptoms and WCST performance

1 reference

12 December 2020

Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia

1 reference

12 December 2020

Association of AKT1 with schizophrenia confirmed in a Japanese population

1 reference

12 December 2020

Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families

1 reference

12 December 2020

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1013535108

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference