Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis. (Q34511187)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20967826%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis (English)

1 reference

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15 February 2020

0 references

6

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15 February 2020

Alessia Omenetti

16

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15 February 2020

David Adams

19

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15 February 2020

Gregory Michelotti

21

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15 February 2020

22

Peter F Whitington

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15 February 2020

author name string

Wing-Kin Syn

1

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15 February 2020

Steve S Choi

2

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15 February 2020

Evaggelia Liaskou

3

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Gamze F Karaca

4

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Kolade M Agboola

5

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Zhiyong Mi

7

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Thiago A Pereira

8

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Marzena Zdanowicz

9

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Padmini Malladi

10

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Yuping Chen

11

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Cynthia Moylan

12

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Youngmi Jung

13

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15 February 2020

Syamal D Bhattacharya

14

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Vanessa Teaberry

15

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Manal F Abdelmalek

17

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Cynthia D Guy

18

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Paul C Kuo

20

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Anna Mae Diehl

23

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language of work or name

English

0 references

publication date

21 October 2010

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15 February 2020

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15 February 2020

volume

53

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15 February 2020

page(s)

106-115

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15 February 2020

issue

1

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Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells

15 February 2020

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1 reference

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Signals from dying hepatocytes trigger growth of liver progenitors

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The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice

7 July 2018

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Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

7 July 2018

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Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.

7 July 2018

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The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin

7 July 2018

1 reference

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Role for hedgehog pathway in regulating growth and function of invariant NKT cells.

7 July 2018

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7 July 2018

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Liver cell-derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells.

7 July 2018

1 reference

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RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells

7 July 2018

1 reference

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Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

7 July 2018

1 reference

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Animal models of NASH: getting both pathology and metabolic context right

7 July 2018

1 reference

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Osteopontin as two-sided mediator of intestinal inflammation

7 July 2018

1 reference

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Corneal wound healing in an osteopontin-deficient mouse

7 July 2018

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The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer

7 July 2018

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Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring

7 July 2018

1 reference

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Osteopontin: role in cell signaling and cancer progression

7 July 2018

1 reference

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Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis

7 July 2018

1 reference

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Effects and regulation of osteopontin in rat hepatic stellate cells

7 July 2018

1 reference

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Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.

7 July 2018

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The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease

7 July 2018

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Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions

7 July 2018

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Impaired angiogenic response in the corneas of mice lacking osteopontin.

7 July 2018

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Osteopontin expression in normal and fibrotic liver. altered liver healing in osteopontin-deficient mice

21 January 2018

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21 January 2018

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Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model

21 January 2018

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21 January 2018

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Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms

21 January 2018

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21 January 2018

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21 January 2018

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Primary culture of cholangiocytes from normal mouse liver

21 January 2018

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12 December 2020

Hepatic stellate cells and fibrosis progression in patients with nonalcoholic fatty liver disease

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12 December 2020

Expression of osteopontin correlates with portal biliary proliferation and fibrosis in biliary atresia

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12 December 2020

In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease

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12 December 2020

Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity

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12 December 2020

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

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12 December 2020

Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression

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12 December 2020

Plasma osteopontin concentration correlates with the severity of hepatic fibrosis and inflammation in HCV-infected subjects

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12 December 2020

Identifiers

DOI

10.1002/HEP.23998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20967826%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20967826%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference