The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity (Q34512981)

2 August 2017

The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity (English)

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2 August 2017

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2

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2 August 2017

4

Gregory J Gores

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2 August 2017

5

Ariel E Feldstein

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2 August 2017

ZhengZheng Li

1

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PubMed ID

18220271

2 August 2017

Thomas M McIntyre

series ordinal

3

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PubMed ID

18220271

2 August 2017

language of work or name

English

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publication date

1 May 2008

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2 August 2017

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2 August 2017

47

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2 August 2017

5

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2 August 2017

1495-1503

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Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Is the slippery slope from steatosis to steatohepatitis paved with triglyceride or cholesterol?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Bax inhibition protects against free fatty acid-induced lysosomal permeabilization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Mitochondria: pharmacological manipulation of cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Nonalcoholic fatty liver disease in the pediatric population: a review

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

The natural history of nonalcoholic fatty liver disease: a population-based cohort study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Apoptotic pathways: ten minutes to dead

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Mitochondrial injury in steatohepatitis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Nonalcoholic steatohepatitis: histologic features and clinical correlations with 30 blinded biopsy specimens

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Mitochondria in nonalcoholic fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Molecular mediators of hepatic steatosis and liver injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

The ins and outs of mitochondrial dysfunction in NASH.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Lipid overload and overflow: metabolic trauma and the metabolic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Lipotoxicity: when tissues overeat

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Nonalcoholic fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Nonalcoholic steatosis and steatohepatitis IV. Nonalcoholic fatty liver disease abnormalities in macrophage function and cytokines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Apoptotic pathways: the roads to ruin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Steatohepatitis: a tale of two "hits"?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025414

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FHEP.22183

Mitochondrial functions during cell death, a complex (I–V) dilemma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FHEP.22183

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FHEP.22183

Studies on fatty acid metabolism in diabetics during exercise. V. Plasma concentration of free fatty acids and glycerol in newly diagnosed, adult diabetics during exercise

21 January 2018

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12 December 2020

1 reference

12 December 2020

Nonalcoholic fatty liver disease

1 reference

12 December 2020

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

1 reference

12 December 2020

Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression

1 reference

12 December 2020

Identifiers

DOI

10.1002/HEP.22183

1 reference

2 August 2017

1 reference

2 August 2017

1 reference

PubMed ID

18220271