Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen (Q34515039)

2 August 2017

title

Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen (English)

1 reference

2 August 2017

1 reference

Claudia Rollenhagen

1

1 reference

2 August 2017

Meike Sörensen

2

1 reference

2 August 2017

Konstantin Rizos

3

1 reference

2 August 2017

Robert Hurvitz

4

1 reference

2 August 2017

Dirk Bumann

5

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 June 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

1 reference

2 August 2017

volume

101

1 reference

2 August 2017

issue

23

1 reference

2 August 2017

page(s)

8739-8744

1 reference

Salmonella flagellin is not a dominant protective antigen in oral immunization with attenuated live vaccine strains

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Single-copy green fluorescent protein gene fusions allow accurate measurement of Salmonella gene expression in vitro and during infection of mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Global analysis of protein expression in yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Epitope dominance, competition and T cell affinity maturation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

The stm4066 gene product of Salmonella enterica serovar Typhimurium has aminoimidazole riboside (AIRs) kinase activity and allows AIRs to satisfy the thiamine requirement of pur mutant strains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Multiparameter selection of Helicobacter pylori antigens identifies two novel antigens with high protective efficacy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Examination of Salmonella gene expression in an infected mammalian host using the green fluorescent protein and two-colour flow cytometry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Epitope tagging of chromosomal genes in Salmonella

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Regulated antigen expression in live recombinant Salmonella enterica serovar Typhimurium strongly affects colonization capabilities and specific CD4(+)-T-cell responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Complete genome sequence of Salmonella enterica serovar Typhimurium LT2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

In vivo visualization of bacterial colonization, antigen expression, and specific T-cell induction following oral administration of live recombinant Salmonella enterica serovar Typhimurium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Salmonella typhimurium thyA mutants fail to grow intracellularly in vitro and are attenuated in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Salmonella typhimurium mutants that downregulate phagocyte nitric oxide production

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

mig-14 is a horizontally acquired, host-induced gene required for salmonella enterica lethal infection in the murine model of typhoid fever

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Novel approaches to monitor bacterial gene expression in infected tissue and host

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Characterization of CD4+ T cell responses during natural infection with Salmonella typhimurium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Modulation of Th2 responses by peptide analogues in a murine model of allergic asthma: amelioration or deterioration of the disease process depends on the Th1 or Th2 skewing characteristics of the therapeutic peptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Safety and immunogenicity of Vi conjugate vaccines for typhoid fever in adults, teenagers, and 2- to 4-year-old children in Vietnam.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Effect of antigen-processing efficiency on in vivo T cell response magnitudes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Cell-specific proteins synthesized by Salmonella typhimurium.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Fluorescence-based isolation of bacterial genes expressed within host cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Bacterial infection as assessed by in vivo gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Invasion of murine intestinal M cells by Salmonella typhimurium inv mutants severely deficient for invasion of cultured cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Urgent need for effective vaccine against Salmonella paratyphi A, B and C.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

FACS-optimized mutants of the green fluorescent protein (GFP)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Salmonella typhimurium aroA- infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines

7 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

7 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

Patterns of protein synthesis in E. coli: a catalog of the amount of 140 individual proteins at different growth rates

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423265

Direct observation of ligand recognition by T cells.

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

Optimization of GFP levels for analyzing Salmonella gene expression during an infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

Use of adoptive transfer of T-cell-antigen-receptor-transgenic T cell for the study of T-cell activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

Correlates of protection induced by live Aro- Salmonella typhimurium vaccines in the murine typhoid model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

Insights into the relation between mrna and protein expression patterns: II. Experimental observations in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

Identification of surface proteins of Helicobacter pylori by selective biotinylation, affinity purification, and two-dimensional gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

Interaction of Salmonella serotypes with porcine macrophages in vitro does not correlate with virulence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401283101

The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15173591

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Two years into reverse vaccinology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15173591

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0401283101

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference