Notch signaling change in pulmonary vascular remodeling in rats with pulmonary hypertension and its implication for therapeutic intervention (Q34516783)

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English	Notch signaling change in pulmonary vascular remodeling in rats with pulmonary hypertension and its implication for therapeutic intervention	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Notch signaling change in pulmonary vascular remodeling in rats with pulmonary hypertension and its implication for therapeutic intervention (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

pulmonary hypertension

1 reference

based on heuristic

inferred from title

microvasculature remodeling

1 reference

based on heuristic

inferred from title

author name string

Lina Qiao

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Liang Xie

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Kun Shi

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Tongfu Zhou

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Yimin Hua

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Hanmin Liu

6

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

0 references

publication date

12 December 2012

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

e51514

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

copyright license

Creative Commons Attribution 4.0 International

12 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Notch2 and Notch3 function together to regulate vascular smooth muscle development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Molecular pathways of notch signaling in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Looking to the future: a new decade of pulmonary arterial hypertension therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Current therapeutics and practical management strategies for pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Influence of Dll4 via HIF-1α-VEGF signaling on the angiogenesis of choroidal neovascularization under hypoxic conditions.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways

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7 July 2018

Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-catenin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch Signaling in the Vasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch3 Is Critical for Proper Angiogenesis and Mural Cell Investment

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Convergence of Notch and beta-catenin signaling induces arterial fate in vascular progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Specification of arterial, venous, and lymphatic endothelial cells during embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch signaling regulates endothelial progenitor cell activity during recovery from arterial injury in hypercholesterolemic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

TGFbeta1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch-RBP-J signaling regulates the mobilization and function of endothelial progenitor cells by dynamic modulation of CXCR4 expression in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch3 signaling promotes the development of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Cellular and molecular basis of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Molecular mechanisms of pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Angiogenic signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Arterial-venous specification during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Regulation of endothelial cell differentiation and arterial specification by VEGF and Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Pathogenic mechanisms of pulmonary arterial hypertension

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Regulation of vascular morphogenesis by Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch signaling in vascular development and physiology

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch signaling in blood vessels: who is talking to whom about what?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Biomechanical regulation of hedgehog signaling in vascular smooth muscle cells in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch signaling.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation by interfering with SRF binding to CArG box

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7 July 2018

Notch signaling from tumor cells: a new mechanism of angiogenesis

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7 July 2018

Essential role of endothelial Notch1 in angiogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch signaling represses myocardin-induced smooth muscle cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Cellular and molecular pathobiology of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Coordinate Notch3-hairy-related transcription factor pathway regulation in response to arterial injury. Mediator role of platelet-derived growth factor and ERK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Notch3 signaling in vascular smooth muscle cells induces c-FLIP expression via ERK/MAPK activation. Resistance to Fas ligand-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Activated Notch4 inhibits angiogenesis: role of beta 1-integrin activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Tumor-promoting phorbol esters induce angiogenesis in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

7 July 2018

Oxygen levels epigenetically regulate fate switching of neural precursor cells via hypoxia-inducible factor 1α-notch signal interaction in the developing brain

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051514

21 January 2018

Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051514

21 January 2018

Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051514

21 January 2018

HRT1 modulates vascular smooth muscle cell proliferation and apoptosis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051514

21 January 2018

Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051514

21 January 2018

Notch-dependent cell cycle arrest is associated with downregulation of minichromosome maintenance proteins.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051514

21 January 2018

A novel mechanism of transcriptional repression of p27kip1 through Notch/HRT2 signaling in vascular smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

27 October 2018

Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3520790

27 October 2018

C-terminal Fragment of Presenilin Is the Molecular Target of a Dipeptidic γ-Secretase-specific Inhibitor DAPT (N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycinet-Butyl Ester)

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051514

21 January 2018

Chronic DLL4 blockade induces vascular neoplasms

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051514

21 January 2018

Changes in osteopontin mRNA expression during phenotypic transition of rabbit arterial smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notch, a universal arbiter of cell fate decisions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regression of hypertrophied rat pulmonary arteries in organ culture is associated with suppression of proteolytic activity, inhibition of tenascin-C, and smooth muscle cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The influence of inhibiting notch signal on pulmonary vascular remodeling induced by PDGF]

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smooth Muscle alpha-actin is a direct target of Notch/CSL

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Effect of inhibition of Notch signal on pulmonary vascular remodeling induced by angiotensin Ⅱ]

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0051514

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

2012PLoSO...751514Q

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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