Normal cells, but not cancer cells, survive severe Plk1 depletion (Q34519883)

2 August 2017

title

Normal cells, but not cancer cells, survive severe Plk1 depletion (English)

1 reference

2 August 2017

Xiaoqi Liu

1

1 reference

2 August 2017

Ming Lei

series ordinal

2

1 reference

2 August 2017

Raymond L Erikson

series ordinal

3

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 March 2006

1 reference

Molecular and Cellular Biology

2 August 2017

published in

1 reference

2 August 2017

volume

26

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2 August 2017

issue

6

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2 August 2017

page(s)

2093-2108

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CCT chaperonin complex is required for the biogenesis of functional Plk1.

2 August 2017

cites work

1 reference

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Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals

7 July 2018

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ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent.

7 July 2018

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7 July 2018

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Polo-like kinases and oncogenesis

7 July 2018

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Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis

7 July 2018

1 reference

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Polo-like kinases and the orchestration of cell division

7 July 2018

1 reference

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Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation

7 July 2018

1 reference

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p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis

7 July 2018

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Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells

7 July 2018

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7 July 2018

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Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA.

7 July 2018

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The polo-like kinase Plx1 is required for activation of the phosphatase Cdc25C and cyclin B-Cdc2 in Xenopus oocytes

7 July 2018

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Metaphase arrest with centromere separation in polo mutants of Drosophila

7 July 2018

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7 July 2018

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Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

7 July 2018

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PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression.

7 July 2018

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Activated polo-like kinase Plx1 is required at multiple points during mitosis in Xenopus laevis

7 July 2018

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Extension of life-span by introduction of telomerase into normal human cells

7 July 2018

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Human Prk is a conserved protein serine/threonine kinase involved in regulating M phase functions

7 July 2018

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Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase

7 July 2018

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Plk is a functional homolog of Saccharomyces cerevisiae Cdc5, and elevated Plk activity induces multiple septation structures

7 July 2018

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Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer.

7 July 2018

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polo, a mitotic mutant of Drosophila displaying abnormal spindle poles.

7 July 2018

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

7 July 2018

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Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

7 July 2018

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Roles of polo-like kinase 1 in the assembly of functional mitotic spindles

7 July 2018

1 reference

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Cancer inhibition in nude mice after systemic application of U6 promoter-driven short hairpin RNAs against PLK1.

27 October 2018

1 reference

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Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts

27 October 2018

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Prognostic value of pololike kinase expression in melanomas

27 October 2018

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12 December 2020

Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells

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12 December 2020

Tumor regression by combination antisense therapy against Plk1 and Bcl-2

1 reference

12 December 2020

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67

1 reference

12 December 2020

Prognostic significance of polo-like kinase (PLK) expression in squamous cell carcinomas of the head and neck

1 reference

12 December 2020

PLK (polo-like kinase), a new prognostic marker for oropharyngeal carcinomas

1 reference

12 December 2020

10.1128/MCB.26.6.2093-2108.2006

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

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