Directed evolution of Her2/neu-binding IgG1-Fc for improved stability and resistance to aggregation by using yeast surface display (Q34522668)

2 August 2017

title

Directed evolution of Her2/neu-binding IgG1-Fc for improved stability and resistance to aggregation by using yeast surface display (English)

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2 August 2017

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Michael W Traxlmayr

1

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2 August 2017

Elisabeth Lobner

2

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2 August 2017

Bernhard Antes

3

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2 August 2017

Manuela Kainer

4

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2 August 2017

Susanne Wiederkum

5

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2 August 2017

Christoph Hasenhindl

6

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2 August 2017

Gerhard Stadlmayr

7

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2 August 2017

Florian Rüker

8

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2 August 2017

Max Woisetschläger

9

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2 August 2017

Kevin Moulder

10

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2 August 2017

Christian Obinger

11

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2 August 2017

publication date

23 December 2012

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Protein Engineering Design and Selection

2 August 2017

published in

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2 August 2017

volume

26

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2 August 2017

issue

4

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2 August 2017

page(s)

255-265

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Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors.

2 August 2017

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Isolating and engineering human antibodies using yeast surface display

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Thermodynamically stable aggregation-resistant antibody domains through directed evolution

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High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method

21 January 2018

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21 January 2018

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Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld.

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Selection for improved protein stability by phage display.

21 January 2018

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21 January 2018

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A modeling analysis of the effects of molecular size and binding affinity on tumor targeting

21 January 2018

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Directed evolution of a stable scaffold for T-cell receptor engineering.

21 January 2018

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Directed evolution of stabilized IgG1-Fc scaffolds by application of strong heat shock to libraries displayed on yeast

21 January 2018

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Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

21 January 2018

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Directed evolution of proteins for increased stability and expression using yeast display

21 January 2018

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Integrin binding human antibody constant domains--probing the C-terminal structural loops for grafting the RGD motif.

21 January 2018

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Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function

21 January 2018

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Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties

21 January 2018

1 reference

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Stabilisation of the Fc fragment of human IgG1 by engineered intradomain disulfide bonds

21 January 2018

1 reference

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Engineering Aggregation Resistance in IgG by Two Independent Mechanisms: Lessons from Comparison of Pichia pastoris and Mammalian Cell Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FPROTEIN%2FGZS102

21 January 2018

Identifiers

DOI

10.1093/PROTEIN/GZS102

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2 August 2017

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