Chemical approaches to the investigation of cellular systems (Q34522697)

2 August 2017

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title

Chemical approaches to the investigation of cellular systems (English)

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2 August 2017

2

Carolyn R Bertozzi

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2 August 2017

Brian N Cook

1

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2 August 2017

language of work or name

English

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publication date

1 April 2002

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Bioorganic & Medicinal Chemistry

2 August 2017

published in

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2 August 2017

volume

10

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2 August 2017

issue

4

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2 August 2017

page(s)

829-840

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Seeing the machinery of live cells

2 August 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

A FLASH of insight into cellular chemistry: genetically encoded labels for protein visualization in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Connexin-aequorin chimerae report cytoplasmic calcium environments along trafficking pathways leading to gap junction biogenesis in living COS-7 cells.

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

The green fluorescent protein

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Dual-colour imaging with GFP variants

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Using GFP in FRET-based applications

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

The structure of the chromophore within DsRed, a red fluorescent protein from coral

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Molecular spectroscopy and dynamics of intrinsically fluorescent proteins: coral red (dsRed) and yellow (Citrine).

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Dynamic and quantitative Ca2+ measurements using improved cameleons

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Alteration of stimulus-specific guard cell calcium oscillations and stomatal closing in Arabidopsis det3 mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Cameleon calcium indicator reports cytoplasmic calcium dynamics in Arabidopsis guard cells

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Organelle pH studies using targeted avidin and fluorescein-biotin

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Specific covalent labeling of recombinant protein molecules inside live cells

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Improved indicators of cell membrane potential that use fluorescence resonance energy transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Direct imaging of DNA in living cells reveals the dynamics of chromosome formation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

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7 January 2021

Caged compounds: tools for illuminating neuronal responses and connections

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

A new caged Ca2+, azid-1, is far more photosensitive than nitrobenzyl-based chelators.

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Small-molecule-based strategies for controlling gene expression

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Specific gain- and loss-of-function phenotypes induced by satellite-specific DNA-binding drugs fed to Drosophila melanogaster.

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Molecular recognition of DNA by small molecules

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

A nonnatural transcriptional coactivator

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Covalent crosslinks introduced via a triple helix-forming oligonucleotide coupled to psoralen are inefficiently repaired

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Controlling gene expression in living cells through small molecule-RNA interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Engineering protein kinases with distinct nucleotide specificities and inhibitor sensitivities by mutation of a single amino acid

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Engineering Src family protein kinases with unnatural nucleotide specificity

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Design of allele-specific inhibitors to probe protein kinase signaling

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

A chemical switch for inhibitor-sensitive alleles of any protein kinase

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Designing small-molecule switches for protein-protein interactions

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Dimerization as a regulatory mechanism in signal transduction

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Chemical genetics resulting from a passion for synthetic organic chemistry.

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Chemical biology beyond binary codes

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Synthesis and activity of bivalent FKBP12 ligands for the regulated dimerization of proteins

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Inducible gene expression and protein translocation using nontoxic ligands identified by a mammalian three-hybrid screen

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Probing the role of homomeric and heteromeric receptor interactions in TGF-beta signaling using small molecule dimerizers

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Unnatural amino acids as probes of protein structure and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

A general method for site-specific incorporation of unnatural amino acids into proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Expanding the genetic code of Escherichia coli

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Site-specific, photochemical proteolysis applied to ion channels in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Flash decaging of tyrosine sidechains in an ion channel.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Engineered cell surfaces: fertile ground for molecular landscaping

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Coumermycin-induced dimerization of GyrB-containing fusion proteins.

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Synthetic ligands point to cell surface strategies

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Glycoprotein-inspired materials promote the proteolytic release of cell surface l-Selectin

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Chemical camouflage of antigenic determinants: stealth erythrocytes

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Engineering chemical reactivity on cell surfaces through oligosaccharide biosynthesis

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Cell surface engineering by a modified Staudinger reaction

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Elongation of the N-acyl side chain of sialic acids in MDCK II cells inhibits influenza A virus infection

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https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Consequences of a subtle sialic acid modification on the murine polyomavirus receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Biochemical engineering of surface alpha 2-8 polysialic acid for immunotargeting tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Biochemical engineering of neural cell surfaces by the synthetic N-propanoyl-substituted neuraminic acid precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Metabolic delivery of ketone groups to sialic acid residues. Application To cell surface glycoform engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

Engineering novel cell surface receptors for virus-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2801%2900376-5

7 January 2021

10.1016/S0968-0896(01)00376-5

Identifiers

DOI

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2 August 2017

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