Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells (Q34524822)

2 August 2017

Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells (English)

1 reference

2 August 2017

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Gabriel C Baltazar

1

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2 August 2017

Sonia Guha

2

1 reference

2 August 2017

Wennan Lu

3

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2 August 2017

Jason Lim

4

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2 August 2017

Kathleen Boesze-Battaglia

5

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2 August 2017

Alan M Laties

6

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2 August 2017

Puneet Tyagi

7

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2 August 2017

Uday B Kompella

8

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2 August 2017

Claire H Mitchell

9

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2 August 2017

language of work or name

English

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publication date

18 December 2012

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2 August 2017

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2 August 2017

7

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2 August 2017

12

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2 August 2017

e49635

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Creative Commons Attribution 4.0 International

2 August 2017

start time

18 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageQuant

object named as

ImageQuant

2 references

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3525582/fullTextXML

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris

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Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells

7 July 2018

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Chloroquine treatment of ARPE-19 cells leads to lysosome dilation and intracellular lipid accumulation: possible implications of lysosomal dysfunction in macular degeneration

7 July 2018

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The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles

7 July 2018

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Applications of nanoparticles in ophthalmology

7 July 2018

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Decoupling internalization, acidification and phagosomal-endosomal/lysosomal fusion during phagocytosis of InlA coated beads in epithelial cells

7 July 2018

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Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV.

7 July 2018

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Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration

7 July 2018

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Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium

7 July 2018

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Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery

7 July 2018

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Stimulation of the P2Y1 receptor up-regulates nucleoside-triphosphate diphosphohydrolase-1 in human retinal pigment epithelial cells.

7 July 2018

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RPE lipofuscin and its role in retinal pathobiology

7 July 2018

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Nanoparticles for gene delivery to retinal pigment epithelial cells.

7 July 2018

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Formation and degradation of poly(D,L-lactide) nanoparticles and their potential application as controllable releasing devices.

7 July 2018

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Retinal pigment epithelial acid lipase activity and lipoprotein receptors: effects of dietary omega-3 fatty acids.

7 July 2018

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Rapid endo-lysosomal escape of poly(DL-lactide-co-glycolide) nanoparticles: implications for drug and gene delivery

7 July 2018

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Probing the cathepsin D using a BODIPY FL-pepstatin A: applications in fluorescence polarization and microscopy

7 July 2018

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Use of the ARPE-19 cell line as a model of RPE polarity: basolateral secretion of FGF5.

7 July 2018

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Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha(v)beta5 integrin for binding but not for internalization

7 July 2018

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Purification, characterization and molecular cloning of human hepatic lysosomal acid lipase

7 July 2018

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Commentary. Lysosomotropic agents

7 July 2018

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Kinetic studies of rod outer segment binding and ingestion by cultured rat RPE cells

7 July 2018

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The basis of antimalarial action: non-weak base effects of chloroquine on acid vesicle pH.

7 July 2018

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Partial purification and properties of acid lipase in the bovine retinal pigment epithelium

7 July 2018

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Studies on the retina and the pigment epithelium in hereditary canine ceroid lipofuscinosis. II. The subcellular distribution of lysosomal hydrolases and other enzymes

7 July 2018

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Inhibition of lysosomal degradation in retinal pigment epithelium cells induces exocytosis of phagocytic residual material at the basolateral plasma membrane

7 July 2018

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Nanobiolistic delivery of indicators to the living mouse retina.

21 January 2018

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The inhibition of death receptor mediated apoptosis through lysosome stabilization following internalization of carboxyfullerene nanoparticles

21 January 2018

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Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles.

21 January 2018

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Degradation of Rod Outer Segment Proteins by Cathepsin D

21 January 2018

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12 December 2020

Acidification of phagosomes and degradation of rod outer segments in rat retinal pigment epithelium

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12 December 2020

Biosynthesis of lysosomal enzymes in fibroblasts. Phosphorylation of mannose residues

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12 December 2020

The phagocytosis of rod outer segments is inhibited by drugs linked to cyclic adenosine monophosphate production

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12 December 2020

A Mechanism for Tamoxifen-mediated Inhibition of Acidification

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12 December 2020

Rod outer segment disc shedding in relation to cyclic lighting

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12 December 2020

Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin

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12 December 2020

10.1371/JOURNAL.PONE.0049635

Identifiers

DOI

1 reference

2 August 2017

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1 reference

2 August 2017

1 reference