ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands (Q34528233)

2 August 2017

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title

ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands (English)

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2 August 2017

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Dwayne G Stupack

1

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2 August 2017

David A Cheresh

series ordinal

2

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2 August 2017

publication date

12 February 2002

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Science's STKE : signal transduction knowledge environment

2 August 2017

published in

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2 August 2017

volume

2002

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2 August 2017

issue

119

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2 August 2017

page(s)

pe7

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Angiogenesis in cancer, vascular, rheumatoid and other disease

2 August 2017

cites work

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A role for angiogenesis in rheumatoid arthritis

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Homeobox B3 promotes capillary morphogenesis and angiogenesis

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Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

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Growth factor-induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen.

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Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

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Affinity of integrins for damaged extracellular matrix: alpha v beta 3 binds to denatured collagen type I through RGD sites

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Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo

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Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5

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The LG3 module of laminin-5 harbors a binding site for integrin alpha3beta1 that promotes cell adhesion, spreading, and migration

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Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis.

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Tissue factor in the heart. Multiple roles in hemostasis, thrombosis, and inflammation

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Effects of thrombin/thrombosis in angiogenesis and tumour progression

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The new human kallikrein gene family: implications in carcinogenesis

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Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor

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Del1 induces integrin signaling and angiogenesis by ligation of alphaVbeta3.

21 January 2018

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Alternative splicing of fibronectin: Three variants, three functions

21 January 2018

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Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform

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Comparison of cell adhesion molecule expression between glioblastoma multiforme and autologous normal brain tissue.

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An angiogenic laminin site and its antagonist bind through the alpha(v)beta3 and alpha5beta1 integrins.

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Role of integrins in angiogenesis

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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Structure, function and biological properties of integrin ?v?3on human melanoma cells

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Differences in laminin fragment interactions of normal and transformed endothelial cells.

21 January 2018

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New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo.

21 January 2018

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Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin

21 January 2018

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Interaction of endostatin with integrins implicated in angiogenesis

21 January 2018

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Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins

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Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions

21 January 2018

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The cell biology of thrombospondin-1.

21 January 2018

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Inhibition of melanoma cell binding to type IV collagen by analogs of cell adhesion regulator

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Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

21 January 2018

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Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

21 January 2018

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Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity

21 January 2018

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Integrin alpha(v)beta(3)-mediated activation of apoptosis

21 January 2018

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Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist.

21 January 2018

1 reference

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Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity

21 January 2018

1 reference

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Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells

21 January 2018

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Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

21 January 2018

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Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

21 January 2018

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NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival

21 January 2018

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Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

21 January 2018

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Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.119.PE7

Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2002.119.PE7

Integrin alphavbeta3 promotes anchorage-dependent apoptosis in human intestinal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.119.PE7

10.1126/STKE.2002.119.PE7

21 January 2018

Identifiers

DOI

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2 August 2017

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