Biomarker-assisted dose selection for safety and efficacy in early development of PNU-100480 for tuberculosis (Q34529109)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078950%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Biomarker-assisted dose selection for safety and efficacy in early development of PNU-100480 for tuberculosis (English)

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16 January 2020

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0 references

8

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16 January 2020

author name string

Robert S Wallis

1

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16 January 2020

Wesley Jakubiec

2

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16 January 2020

Vikas Kumar

3

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16 January 2020

Gabriella Bedarida

4

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16 January 2020

Annette Silvia

5

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16 January 2020

Darcy Paige

6

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16 January 2020

Tong Zhu

7

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16 January 2020

Lynn Ladutko

9

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16 January 2020

Sheldon Campbell

10

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16 January 2020

Paul F Miller

11

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16 January 2020

language of work or name

English

0 references

publication date

15 November 2010

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Antimicrobial Agents and Chemotherapy

16 January 2020

published in

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16 January 2020

volume

55

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16 January 2020

issue

2

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16 January 2020

page(s)

567-574

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Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice

16 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Linezolid use for treatment of multidrug-resistant and extensively drug-resistant tuberculosis, New York City, 2000-06.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Strain specificity of antimycobacterial immunity in whole blood culture after cure of tuberculosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

A retrospective TBNET assessment of linezolid safety, tolerability and efficacy in multidrug-resistant tuberculosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Promising antituberculosis activity of the oxazolidinone PNU-100480 relative to that of linezolid in a murine model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Efficacy and tolerability of daily-half dose linezolid in patients with intractable multidrug-resistant tuberculosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Linezolid for the treatment of multidrug-resistant tuberculosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Efficacy and safety of linezolid in multidrug resistant tuberculosis (MDR-TB)--a report of ten cases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Survival and replication of clinical Mycobacterium tuberculosis isolates in the context of human innate immunity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Lack of activity of orally administered clofazimine against intracellular Mycobacterium tuberculosis in whole-blood culture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

The curious characteristics of pyrazinamide: a review

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Thrombocytopenia associated with linezolid therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Activities of several novel oxazolidinones against Mycobacterium tuberculosis in a murine model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Pharmacokinetics and whole-blood bactericidal activity against Mycobacterium tuberculosis of single doses of PNU-100480 in healthy volunteers.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Assessment of linezolid efficacy and safety in MDR- and XDR-TB: an Indian perspective

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Addition of PNU-100480 to first-line drugs shortens the time needed to cure murine tuberculosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Daily 300 mg dose of linezolid for the treatment of intractable multidrug-resistant and extensively drug-resistant tuberculosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Daily half-dose linezolid for the treatment of intractable multidrug-resistant tuberculosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Case series report of a linezolid-containing regimen for extensively drug-resistant tuberculosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Linezolid in the treatment of 'difficult' multidrug-resistant tuberculosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Post-antibiotic effects of linezolid and other agents against Mycobacterium tuberculosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

A whole blood bactericidal assay for tuberculosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

Whole Blood Bactericidal Activity during Treatment of Pulmonary Tuberculosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028776

9 December 2018

Identifiers

DOI

10.1128/AAC.01179-10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078950%20AND%20SRC:MED&resulttype=core&format=json

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16 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/ngj7awvbpbfk7d2gvfdalwulae

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078950%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference