A working model for the time sequence of genetic changes in breast tumorigenesis (Q34534165)

2 August 2017

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title

A working model for the time sequence of genetic changes in breast tumorigenesis (English)

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2 August 2017

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1

S Eva Singletary

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2 August 2017

language of work or name

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1 February 2002

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Journal of the American College of Surgeons

2 August 2017

published in

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2 August 2017

volume

194

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2 August 2017

issue

2

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2 August 2017

page(s)

202-216

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Adjuvant tamoxifen versus placebo in elderly women with node-positive breast cancer: long-term follow-up and causes of death

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Genetic alterations during colorectal-tumor development

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cancer and ageing in mice and men

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Risk factors for breast cancer in women with proliferative breast disease

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

RELATIONSHIP OF FIBROCYSTIC DISEASE TO CARCINOMA OF THE BREAST

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Atypical epithelial hyperplasia associated with breast cancer and fibrocystic disease

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The transition from hyperplasia to invasive carcinoma of the breast

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Prevalence of benign, atypical, and malignant breast lesions in populations at different risk for breast cancer. A forensic autopsy study

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Molecular genetic studies of early breast cancer evolution

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Intraductal carcinoma of the breast: Follow-up after biopsy only

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Immunocytochemical demonstration and significance of p21 ras family oncogene product in benign and malignant breast disease

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Immunohistochemical detection of ras oncogene p21 product in benign and malignant mammary tissue in man.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Expression of ras oncogene p21 protein in relation to regional spread of human breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Ras activation in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Amplification of growth regulatory genes in intraductal breast cancer is associated with higher nuclear grade but not with the progression to invasiveness.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Genetic alterations on chromosome 16 and 17 are important features of ductal carcinoma in situ of the breast and are associated with histologic type

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

C-myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Mutation and cancer: statistical study of retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

p53: tumor suppression through control of the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

bcl-2: role in epithelial differentiation and oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Tumor suppressor genes and their alterations in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

p53 mutations in benign breast tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Modulation of biomarkers in minimal breast carcinoma: a model for human breast carcinoma progression

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Retinoblastoma and p53 gene product expression in breast carcinoma: immunohistochemical analysis and clinicopathologic correlation

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Tumor suppressor genes and their roles in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Expression of the antimetastatic gene nm23 in human breast cancer: an association with good prognosis

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Genetic changes in breast cancer -consequences for therapy?

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

HER-2/neu amplification in benign breast disease and the risk of subsequent breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The relationship between human epidermal growth-like factor receptor expression and cellular transformation in NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Epidermal growth factor-related peptides in the pathogenesis of human breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cripto: a novel epidermal growth factor (EGF)-related peptide in mammary gland development and neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Detection of amphiregulin and Cripto-1 in mammary tumors from transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Neu and its ligands: from an oncogene to neural factors

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cell cycle control and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cdk inhibitors: on the threshold of checkpoints and development

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Growth suppression by p16ink4 requires functional retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Deregulated cyclin E induces chromosome instability

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Lack of cyclin E immunoreactivity in non-malignant breast and association with proliferation in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cyclin D1 expression in ductal carcinoma in situ, atypical ductal hyperplasia and usual ductal hyperplasia: an immunohistochemical study.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cyclin E, a redundant cyclin in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cyclin D1 overexpression in a model of human breast premalignancy: preferential stimulation of anchorage-independent but not anchorage-dependent growth is associated with increased cdk2 activity

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Expression of proliferation and apoptosis-related proteins in usual ductal hyperplasia of the breast.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cyclin D1 and associated proteins in mammary ductal carcinoma in situ and atypical ductal hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Cyclins and breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

bcl-2 expression in normal breast tissue during the menstrual cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

bcl-2 expression in the spectrum of preinvasive breast lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Is there a role for molecular prognostic factors in the clinical management of ductal carcinoma in situ (DCIS) of the breast?

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Loss of bcl-2 expression in ductal carcinoma in situ of the breast relates to poor histological differentiation and to expression of p53 and c-erbB-2 proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The extent of proliferative and apoptotic activity in intraductal and invasive ductal breast carcinomas detected by Ki-67 labeling and terminal deoxynucleotidyl transferase-mediated digoxigenin-11-dUTP nick end labeling

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

MIB-1 Proliferation Index in Ductal Carcinoma In Situ of the Breast: Relationship to the Expression of the Apoptosis-Regulating Proteins bcl-2 and p53

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Evidence of significant apoptosis in poorly differentiated ductal carcinoma in situ of the breast

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The pathway of neoplastic transformation of human breast epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

A new diploid nontumorigenic human breast epithelial cell line isolated and propagated in chemically defined medium.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Multiple genetic changes are required for efficient immortalization of different subtypes of normal human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Critical steps in breast carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Microsatellite instability during the immortalization and transformation of human breast epithelial cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

The p53 tumour suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Evidence implicating at least two genes on chromosome 17p in breast carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Detailed analysis of loss of heterozygosity on chromosome band 17p13 in breast carcinoma on the basis of a high-resolution physical map with 29 markers

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Differential display of reticulocalbin in the highly invasive cell line, MDA-MB-435, versus the poorly invasive cell line, MCF-7.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Differentiation state and invasiveness of human breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Biologic markers in ductal carcinoma in situ and concurrent infiltrating carcinoma. A comparison of eight contemporary grading systems

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Differentially expressed genes associated with the metastatic phenotype in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in patients with ductal carcinoma in situ of the breast

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Expression of metastasis-associated genes h-mts1 (S100A4) and nm23 in carcinoma of breast is related to disease progression.

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

Evaluation of the predictive value of Her-2/neu overexpression and p53 mutations in high-risk primary breast cancer patients treated with high-dose chemotherapy and autologous stem-cell transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS1072-7515%2801%2901108-5

7 January 2021

10.1016/S1072-7515(01)01108-5

Identifiers

DOI

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2 August 2017

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