Variable region sequences of a protective human monoclonal antibody specific for the Haemophilus influenzae type b capsular polysaccharide (Q34537160)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8063404%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

title

Variable region sequences of a protective human monoclonal antibody specific for the Haemophilus influenzae type b capsular polysaccharide (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8063404%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

1 reference

1 reference

Haemophilus influenzae

object named as

Haemophilus influenzae

1 reference

1 reference

A H Lucas

1

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24 October 2019

J W Larrick

series ordinal

2

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24 October 2019

D C Reason

series ordinal

3

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24 October 2019

language of work or name

English

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publication date

1 September 1994

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24 October 2019

published in

Infection and Immunity

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24 October 2019

volume

62

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24 October 2019

issue

9

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24 October 2019

page(s)

3873-3880

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Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus

24 October 2019

cites work

1 reference

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Variable region expression in the antibody responses of infants vaccinated with Haemophilus influenzae type b polysaccharide-protein conjugates. Description of a new lambda light chain-associated idiotype and the relation between idiotype expression

7 July 2018

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High-frequency representation of a single VH gene in the expressed human B cell repertoire

7 July 2018

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Mechanisms that generate human immunoglobulin diversity operate from the 8th week of gestation in fetal liver

7 July 2018

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The human VH3b gene subfamily is highly polymorphic

7 July 2018

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7 July 2018

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Isoelectric focusing of human antibody to the Haemophilus influenzae b capsular polysaccharide: restricted and identical spectrotypes in adults.

7 July 2018

1 reference

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DNA sequence analysis with a modified bacteriophage T7 DNA polymerase

7 July 2018

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Organization of human immunoglobulin heavy chain diversity gene loci

7 July 2018

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Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy

7 July 2018

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Isolation and characterization of human VkIII germ-line genes. Implications for the molecular basis of human VkIII light chain diversity

7 July 2018

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Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies

7 July 2018

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Polysaccharide-protein conjugate vaccines for the prevention of Haemophilus influenzae type b disease

7 July 2018

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Wound macrophages express TGF-alpha and other growth factors in vivo: analysis by mRNA phenotyping

7 July 2018

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A conserved human germline V kappa gene directly encodes rheumatoid factor light chains

7 July 2018

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Functional affinity of antibody to the Haemophilus influenzae type b polysaccharide

7 July 2018

1 reference

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Ig V region gene expression in small lymphocytic lymphoma with little or no somatic hypermutation

7 July 2018

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Molecular characterization of a major autoantibody-associated cross-reactive idiotype in Sjogren's syndrome

7 July 2018

1 reference

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Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. II. IgG antibodies contain VH genes from a single VH family and VL genes from at least four VL families.

7 July 2018

1 reference

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The recurrent expression of variable region segments in human IgM anti-DNA autoantibodies.

7 July 2018

1 reference

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Complete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family

7 July 2018

1 reference

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A major crossreactive idiotype associated with human antibodies to the Haemophilus influenzae b polysaccharide. Expression in relation to age and immunoglobulin G subclass

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303043

Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. IV. The less frequently expressed VL are heterogeneous.

7 July 2018

1 reference

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Variable region diversity in human circulating antibodies specific for the capsular polysaccharide of Haemophilus influenzae type b. Preferential usage of two types of VH3 heavy chains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303043

Restricted Ig H chain V gene usage in the human antibody response to Haemophilus influenzae type b capsular polysaccharide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303043

Human immunoglobulin heavy-chain variable region genes: organization, polymorphism, and expression

7 July 2018

1 reference

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Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes

7 July 2018

1 reference

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An idiotypic marker associated with a germ-line encoded kappa light chain variable region that predominates the vaccine-induced human antibody response to the Haemophilus influenzae b polysaccharide

7 July 2018

1 reference

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Evaluation of bacterial polysaccharide immune globulin for the treatment or prevention of Haemophilus influenzae type b and pneumococcal disease

7 July 2018

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Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes

7 July 2018

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Evidence for somatic selection of natural autoantibodies

7 July 2018

1 reference

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Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303043

The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

7 July 2018

1 reference

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Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody

7 July 2018

1 reference

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Sequence analyses of three immunoglobulin G anti-virus antibodies reveal their utilization of autoantibody-related immunoglobulin Vh genes, but not V lambda genes

7 July 2018

1 reference

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Therapeutic Human Antibodies Derived from PCR Amplification of B‐Cell Variable Regions

7 July 2018

1 reference

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DNA sequencing with chain-terminating inhibitors

7 July 2018

1 reference

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Induction of immunologic memory in infants primed with Haemophilus influenzae type b conjugate vaccines.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303043

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303043

Age-associated changes in binding of human B lymphocytes to a VH3-restricted unconventional bacterial antigen.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303043

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303043

Quantitative measurement of "natural" and immunization-induced Haemophilus influenzae type b capsular polysaccharide antibodies

27 October 2018

1 reference

12 December 2020

Restricted light chain subgroup expression on human rheumatoid factor paraproteins determined by monoclonal antibodies

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12 December 2020

The human VK locus. Characterization of a duplicated region encoding 28 different immunoglobulin genes

1 reference

12 December 2020

Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. III. A single VKII gene and one of several JK genes are joined by an invariant arginine to form the most common L chain V region

1 reference

12 December 2020

Bactericidal and opsonic activity of IgG1 and IgG2 anticapsular antibodies to Haemophilus influenzae type b

1 reference

12 December 2020

Comparative trial in infants of four conjugate Haemophilus influenzae type b vaccines

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12 December 2020

Avidity and bactericidal activity of antibody elicited by different Haemophilus influenzae type b conjugate vaccines. The Vaccine Study Group

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12 December 2020

Differences in the immunogenicity of three Haemophilus influenzae type b conjugate vaccines in infants

1 reference

12 December 2020

Rapid disappearance of Haemophilus influenzae type b meningitis after routine childhood immunisation with conjugate vaccines

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12 December 2020

Declining incidence of Haemophilus influenzae type b disease since introduction of vaccination

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12 December 2020

Age-dependent V region expression in the human antibody response to the Haemophilus influenzae type b polysaccharide

1 reference

12 December 2020

Restricted immunoglobulin VH usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of monospecific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with

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Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8063404%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

PubMed publication ID

8063404

1 reference