Cdc7 kinase complex: a key regulator in the initiation of DNA replication (Q34539989)

2 August 2017

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title

Cdc7 kinase complex: a key regulator in the initiation of DNA replication (English)

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2 August 2017

Hisao Masai

1

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PubMed ID

11857444

2 August 2017

Ken-Ichi Arai

series ordinal

2

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2 August 2017

1 March 2002

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Journal of Cellular Physiology

2 August 2017

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2 August 2017

190

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2 August 2017

3

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2 August 2017

287-296

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A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast

2 August 2017

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Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

21 January 2018

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Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint

21 January 2018

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ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

21 January 2018

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The Cdc7 protein kinase is required for origin firing during S phase

21 January 2018

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Duplex opening by dnaA protein at novel sequences in initiation of replication at the origin of the E. coli chromosome

21 January 2018

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A model for initiation at origins of DNA replication

21 January 2018

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Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast

21 January 2018

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Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase

21 January 2018

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CDC7 protein kinase activity is required for mitosis and meiosis in Saccharomyces cerevisiae

21 January 2018

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Animal virus DNA replication

21 January 2018

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Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage.

21 January 2018

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Cdc7 is required throughout the yeast S phase to activate replication origins.

21 January 2018

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Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo.

21 January 2018

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Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex

21 January 2018

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hCDC47, a Human Member of the MCM Family

21 January 2018

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Cell cycle- and chromatin binding state-dependent phosphorylation of human MCM heterohexameric complexes. A role for cdc2 kinase.

21 January 2018

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Enzymatic replication of the origin of the Escherichia coli chromosome

21 January 2018

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Premature structural changes at replication origins in a yeast minichromosome maintenance (MCM) mutant

21 January 2018

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Cloning and characterization of Chinese hamster homologue of yeast DBF4 (ChDBF4)

21 January 2018

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

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A novel role for Cdc5p in DNA replication

21 January 2018

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mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p

21 January 2018

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Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex

21 January 2018

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A group of interacting yeast DNA replication genes

21 January 2018

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Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication

21 January 2018

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Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2

21 January 2018

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A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

21 January 2018

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Phosphorylation of Mcm4 at specific sites by cyclin-dependent kinase leads to loss of Mcm4,6,7 helicase activity

21 January 2018

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Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2

21 January 2018

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Biochemical activities associated with mouse Mcm2 protein

21 January 2018

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Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

21 January 2018

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Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein

21 January 2018

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The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?

21 January 2018

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Identification and characterization of a human protein kinase related to budding yeast Cdc7p

21 January 2018

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Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

21 January 2018

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First the CDKs, now the DDKs

21 January 2018

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Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication

21 January 2018

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Characterization of the yeast Cdc7p/Dbf4p complex purified from insect cells. Its protein kinase activity is regulated by Rad53p

21 January 2018

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Growth regulation of the expression of mouse cDNA and gene encoding a serine/threonine kinase related to Saccharomyces cerevisiae CDC7 essential for G1/S transition. Structure, chromosomal localization, and expression of mouse gene for s. cerevisiae

21 January 2018

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Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor

21 January 2018

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A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells

21 January 2018

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Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures

21 January 2018

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Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis

21 January 2018

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Identification, characterization and chromosomal localization of the cognate human and murine DBF4 genes

21 January 2018

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Dbf4 motifs: conserved motifs in activation subunits for Cdc7 kinases essential for S-phase

21 January 2018

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Regulation of DNA replication during the cell cycle: roles of Cdc7 kinase and coupling of replication, recombination, and repair in response to replication fork arrest

21 January 2018

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21 January 2018

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Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast

21 January 2018

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The Schizosaccharomyces pombe spo6+ gene encoding a nuclear protein with sequence similarity to budding yeast Dbf4 is required for meiotic second division and sporulation.

21 January 2018

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Novel fission yeast Cdc7-Dbf4-like kinase complex required for the initiation and progression of meiotic second division

21 January 2018

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Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation

21 January 2018

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Bipartite binding of a kinase activator activates Cdc7-related kinase essential for S phase

21 January 2018

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Analyses of Saccharomyces cerevisiae Cdc7 kinase point mutants: dominant-negative inhibition of DNA replication on overexpression of kinase-negative Cdc7 proteins.

21 January 2018

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Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability.

21 January 2018

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Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae

21 January 2018

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DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase

21 January 2018

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Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7

21 January 2018

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Electron microscopic observation and single-stranded DNA binding activity of the Mcm4,6,7 complex.

21 January 2018

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Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication

21 January 2018

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Differential regulation of the yeast CDC7 gene during mitosis and meiosis

21 January 2018

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Oligomers of the Cdc7/Dbf4 protein kinase exist in the yeast cell.

21 January 2018

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G1 phase progression: cycling on cue

21 January 2018

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Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity.

21 January 2018

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Cell cycle control of DNA replication.

21 January 2018

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A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage

21 January 2018

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Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast

21 January 2018

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Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases

21 January 2018

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The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides

21 January 2018

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MCM proteins in DNA replication

21 January 2018

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Essential role of Sna41/Cdc45 in loading of DNA polymerase alpha onto minichromosome maintenance proteins in fission yeast.

21 January 2018

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Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts.

21 January 2018

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Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway

21 January 2018

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The CDC7 protein of Saccharomyces cerevisiae is a phosphoprotein that contains protein kinase activity

21 January 2018

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Regulation of Saccharomyces cerevisiae CDC7 function during the cell cycle

21 January 2018

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Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.10070

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2 August 2017

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PubMed ID

11857444