A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E (Q34541330)

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English	A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E	scientific article

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scholarly article

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Europe PubMed Central

2 August 2017

A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E (English)

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Europe PubMed Central

2 August 2017

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Francis M. Ndungu

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Francis M Ndungu

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9

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Philip Bejon

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Europe PubMed Central

2 August 2017

8

object named as

Ally Olotu

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Europe PubMed Central

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7

object named as

Johan Vekemans

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Europe PubMed Central

2 August 2017

author name string

Jedidah Mwacharo

2

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Europe PubMed Central

2 August 2017

Domtila Kimani

3

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Europe PubMed Central

2 August 2017

Oscar Kai

4

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Europe PubMed Central

2 August 2017

Philippe Moris

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Europe PubMed Central

2 August 2017

Erik Jongert

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Europe PubMed Central

2 August 2017

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publication date

27 December 2012

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

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Europe PubMed Central

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12

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Europe PubMed Central

2 August 2017

e52870

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Europe PubMed Central

2 August 2017

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Creative Commons Attribution 4.0 International

27 December 2012

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April 2022 Public Data File from Crossref

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Use of massively parallel pyrosequencing to evaluate the diversity of and selection on Plasmodium falciparum csp T-cell epitopes in Lilongwe, Malawi

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Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine

1 reference

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7 July 2018

Expanding roles for CD4⁺ T cells in immunity to viruses.

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7 July 2018

Longevity and composition of cellular immune responses following experimental Plasmodium falciparum malaria infection in humans

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7 July 2018

Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria

1 reference

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7 July 2018

Safety and efficacy of the RTS, S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

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7 July 2018

Protective immunity induced with the RTS,S/AS vaccine is associated with IL-2 and TNF-α producing effector and central memory CD4 T cells

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Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults

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Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children

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T cell responses to the RTS,S/AS01e and RTS,S/AS02D malaria candidate vaccines administered according to different schedules to Ghanaian children

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Recent clinical experience with vaccines using MPL- and QS-21-containing adjuvant systems

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Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

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Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations

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Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

1 reference

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7 July 2018

The RTS,S malaria vaccine

1 reference

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Differential effector pathways regulate memory CD8 T cell immunity against Plasmodium berghei versus P. yoelii sporozoites.

1 reference

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Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

1 reference

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Insights into long-lasting protection induced by RTS,S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican children

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Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

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Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants

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GlaxoSmithKline Adjuvant Systems in vaccines: concepts, achievements and perspectives

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The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum

1 reference

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Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial

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Differential evidence of natural selection on two leading sporozoite stage malaria vaccine candidate antigens

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RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection

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Calculation of liver-to-blood inocula, parasite growth rates, and preerythrocytic vaccine efficacy, from serial quantitative polymerase chain reaction studies of volunteers challenged with malaria sporozoites

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Protective efficacy of the RTS,S/AS02 Plasmodium falciparum malaria vaccine is not strain specific

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Unique T cell effector functions elicited by Plasmodium falciparum epitopes in malaria-exposed Africans tested by three T cell assays.

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Efficacy of recombinant circumsporozoite protein vaccine regimens against experimental Plasmodium falciparum malaria.

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Protection against malaria by Plasmodium yoelii sporozoite surface protein 2 linear peptide induction of CD4+ T cell- and IFN-gamma-dependent elimination of infected hepatocytes.

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Anti-Sporozoite Antibodies Induced by Natural Infection *

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052870

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Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans

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A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052870

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Novel protein and poxvirus-based vaccine combinations for simultaneous induction of humoral and cell-mediated immunity.

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21 January 2018

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10.1371/JOURNAL.PONE.0052870

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Europe PubMed Central

2 August 2017

2012PLoSO...752870N

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

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