Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening. (Q34543062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23302687%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening (English)

1 reference

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21 February 2020

1 reference

1

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21 February 2020

2

Sean F Brady

1 reference

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21 February 2020

language of work or name

English

0 references

publication date

9 January 2013

1 reference

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21 February 2020

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

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21 February 2020

volume

110

1 reference

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21 February 2020

issue

7

1 reference

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21 February 2020

page(s)

2478-2483

1 reference

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Biosynthetic gene cluster for the cladoniamides, bis-indoles with a rearranged scaffold

21 February 2020

cites work

1 reference

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Cloning and characterization of an environmental DNA-derived gene cluster that encodes the biosynthesis of the antitumor substance BE-54017.

7 July 2018

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Accessing the hidden majority of marine natural products through metagenomics

7 July 2018

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Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis

7 July 2018

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Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products

7 July 2018

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Shared Biosynthesis of the Saliniketals and Rifamycins in Salinispora arenicola is Controlled by the sare1259-Encoded Cytochrome P450

7 July 2018

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Divergent pathways in the biosynthesis of bisindole natural products

7 July 2018

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The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

7 July 2018

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Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine

7 July 2018

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Construction of soil environmental DNA cosmid libraries and screening for clones that produce biologically active small molecules

7 July 2018

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Indolocarbazole natural products: occurrence, biosynthesis, and biological activity

7 July 2018

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Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase

7 July 2018

1 reference

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Membrane estrogen receptor-alpha levels in MCF-7 breast cancer cells predict cAMP and proliferation responses

7 July 2018

1 reference

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The role of the novel Fem protein VanK in vancomycin resistance in Streptomyces coelicolor

7 July 2018

1 reference

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Nonribosomal peptides: from genes to products

7 July 2018

1 reference

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Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574908

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

7 July 2018

1 reference

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Genetic Contributions to Understanding Polyketide Synthases

7 July 2018

1 reference

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Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product

7 July 2018

1 reference

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A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

7 July 2018

1 reference

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Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica

7 July 2018

1 reference

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Production and biological activity of rebeccamycin, a novel antitumor agent.

7 July 2018

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High diversity in DNA of soil bacteria

7 July 2018

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Rediscovery of known natural compounds: nuisance or goldmine?

7 July 2018

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The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives

21 January 2018

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Cryptic carbapenem antibiotic production genes are widespread in Erwinia carotovora: facile trans activation by the carR transcriptional regulator

21 January 2018

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Synthesis and assignment of the absolute configuration of indenotryptoline bisindole alkaloid BE-54017.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218073110

Hypoxia-inducible factor-1 confers resistance to the glycolytic inhibitor 2-deoxy-D-glucose

21 January 2018

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DNA binding properties of the marine sponge pigment fascaplysin

21 January 2018

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New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity

21 January 2018

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Calcium/calmodulin-dependent kinase II plays an important role in prostate cancer cell survival

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23302687

12 December 2020

inferred from PubMed ID database lookup

Novel tetrahydro-beta-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23302687

12 December 2020

inferred from PubMed ID database lookup

Cladoniamides A−G, Tryptophan-Derived Alkaloids Produced in Culture byStreptomyces uncialis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23302687

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1218073110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23302687%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

0 references

1 reference

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21 February 2020

PubMed publication ID

23302687

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23302687%20AND%20SRC:MED&resulttype=core&format=json