Reduced expression of IL-12 p35 by SJL/J macrophages responding to Theiler's virus infection is associated with constitutive activation of IRF-3. (Q34545275)

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English	Reduced expression of IL-12 p35 by SJL/J macrophages responding to Theiler's virus infection is associated with constitutive activation of IRF-3.	scientific article

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Reduced expression of IL-12 p35 by SJL/J macrophages responding to Theiler's virus infection is associated with constitutive activation of IRF-3. (English)

1 reference

Europe PubMed Central

2 August 2017

author name string

Angela Dahlberg

1

1 reference

Europe PubMed Central

2 August 2017

Mark R Auble

2

1 reference

Europe PubMed Central

2 August 2017

Thomas M Petro

3

1 reference

Europe PubMed Central

2 August 2017

language of work or name

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publication date

7 July 2006

1 reference

Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

353

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Europe PubMed Central

2 August 2017

2

1 reference

Europe PubMed Central

2 August 2017

422-432

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Europe PubMed Central

2 August 2017

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

1 reference

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Bone marrow chimeras reveal non-H-2 hematopoietic control of susceptibility to Theiler's virus persistent infection

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Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

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Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes

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IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis.

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Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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The leader protein of Theiler's virus interferes with nucleocytoplasmic trafficking of cellular proteins

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Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin

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Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

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The role of Toll-like receptor 4 versus interleukin-12 in immunity to respiratory syncytial virus

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Assembly of a functional beta interferon enhanceosome is dependent on ATF-2-c-jun heterodimer orientation

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

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A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

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Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation

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IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

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Role of the IL-12/IL-23 system in the regulation of T-cell responses in central nervous system inflammatory demyelination

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

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Role of Toll-like receptors in pathogen recognition.

1 reference

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Functional characterization of interferon regulatory factor 3a (IRF-3a), an alternative splice isoform of IRF-3.

1 reference

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Mouse hepatitis virus type 4 (JHM strains). induced fatal central nervous system disease. I. genetic control and murine neuron as the susceptible site of disease

1 reference

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7 January 2021

IRF-1 and NF-kappaB p50/cRel bind to distinct regions of the proximal murine IL-12 p35 promoter during costimulation with IFN-gamma and LPS.

1 reference

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Deletional analysis of the murine IL-12 p35 promoter comparing IFN-gamma and lipopolysaccharide stimulation

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Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains

1 reference

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Theiler's virus persistence in the central nervous system of mice is associated with continuous viral replication and a difference in outcome of infection of infiltrating macrophages versus oligodendrocytes

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Genetic control of resistance to street rabies virus in mice

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Induction and regulation of IFNs during viral infections

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Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

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Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

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Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection

1 reference

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Short-term treatment with interferon-alpha/beta promotes remyelination, whereas long-term treatment aggravates demyelination in a murine model of multiple sclerosis

1 reference

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Theiler's virus infection: a model for multiple sclerosis

1 reference

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A virus-induced molecular mimicry model of multiple sclerosis

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

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Induction of nitric-oxide synthase and activation of NF-kappaB by interleukin-12 p40 in microglial cells

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Disparate expression of IL-12 by SJL/J and B10.S macrophages during Theiler's virus infection is associated with activity of TLR7 and mitogen-activated protein kinases

1 reference

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Regulation of type I interferon gene expression by interferon regulatory factor-3.

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Multiple signaling pathways leading to the activation of interferon regulatory factor 3.

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IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29.

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An altered immune response to Epstein-Barr virus in multiple sclerosis: a prospective study

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Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

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Toll-like receptors in innate immunity

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The leader protein of Theiler's virus inhibits immediate-early alpha/beta interferon production

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Tmevpg1, a candidate gene for the control of Theiler's virus persistence, could be implicated in the regulation of gamma interferon.

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Genetic analysis of multiple sclerosis

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Hantaan virus infection causes an acute neurological disease that is fatal in adult laboratory mice

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10.1016/J.VIROL.2006.05.034

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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