Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans (Q34546846)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15768052%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans (English)

1 reference

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Erratum: Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans

9 January 2020

corrigendum / erratum

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author

Peter K. Rogan

8

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9 January 2020

author name string

A Gaedigk

1

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9 January 2020

A Bhathena

2

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9 January 2020

L Ndjountché

3

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9 January 2020

R E Pearce

4

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9 January 2020

S M Abdel-Rahman

5

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9 January 2020

S W Alander

6

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9 January 2020

L DiAnne Bradford

7

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9 January 2020

J Steven Leeder

9

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9 January 2020

publication date

1 January 2005

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The Pharmacogenomics Journal

9 January 2020

published in

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9 January 2020

volume

5

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9 January 2020

issue

3

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9 January 2020

page(s)

173-182

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Pharmacogenetics and the regulation of gene transcription

9 January 2020

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7 July 2018

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7 July 2018

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Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes

7 July 2018

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7 July 2018

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Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data

7 July 2018

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Comparison of three CYP2D6 probe substrates and genotype in Ghanaians, Chinese and Caucasians

7 July 2018

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7 July 2018

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Information analysis of human splice site mutations

21 January 2018

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Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences

7 July 2018

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Phenotype and genotype analysis of debrisoquine hydroxylase (CYP2D6) in a black Zimbabwean population. Reduced enzyme activity and evaluation of metabolic correlation of CYP2D6 probe drugs

7 July 2018

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Characterization of the human cytochrome P4502D6 promoter. A potential role for antagonistic interactions between members of the nuclear receptor family

7 July 2018

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Debrisoquine and metoprolol oxidation in Zambians: a population study

7 July 2018

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The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene

7 July 2018

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Evidence for a dissociation in the control of sparteine, debrisoquine and metoprolol metabolism in Nigerians

7 July 2018

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Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase

7 July 2018

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Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine.

21 January 2018

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Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population

21 January 2018

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21 January 2018

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Comparison of two CYP2D6 genotyping methods and assessment of genotype-phenotype relationships

27 October 2018

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Characterization of (+/-)-bufuralol hydroxylation activities in liver microsomes of Japanese and Caucasian subjects genotyped for CYP2D6.

21 January 2018

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New allelic arrangement CYP2D6*36 x 2 found in a Japanese poor metabolizer of debrisoquine

21 January 2018

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Analysis of the CYP2D6 gene polymorphism and enzyme activity in African-Americans in southern California

21 January 2018

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CYP2D6 poor metabolizer status can be ruled out by a single genotyping assay for the -1584G promoter polymorphism

21 January 2018

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Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation

21 January 2018

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Information theory-based analysis of CYP2C19, CYP2D6 and CYP3A5 splicing mutations.

21 January 2018

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Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden

21 January 2018

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Discovery of a novel nonfunctional cytochrome P450 2D6 allele, CYP2D642, in African American subjects

21 January 2018

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

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A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects.

21 January 2018

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Investigation of terbinafine as a CYP2D6 inhibitor in vivo.

21 January 2018

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Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquine

21 January 2018

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Genetic polymorphisms of CYP2D6 in Chinese mainland.

21 January 2018

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Analysis of the CYP2D6 gene mutations and their consequences for enzyme function in a West African population

27 October 2018

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CYP2D6 phenotype-genotype relationships in African-Americans and Caucasians in Los Angeles.

27 October 2018

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Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6

27 October 2018

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12 December 2020

G169R mutation diminishes the metabolic activity of CYP2D6 in Chinese

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12 December 2020

A new variant CYP2D6 allele (CYP2D6*21) with a single base insertion in exon 5 in a Japanese population associated with a poor metabolizer phenotype

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12 December 2020

PCR-based genotyping for duplicated and deleted CYP2D6 genes

1 reference

12 December 2020

A new CYP2D6 allele with a nine base insertion in exon 9 in a Japanese population associated with poor metabolizer phenotype

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12 December 2020

Identifiers

DOI

10.1038/SJ.TPJ.6500305

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15768052%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 January 2020

1005104523

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Fatcat ID

release_6nm7meumd5fttiybgm7up47iye

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15768052%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

15768052

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reason for deprecated rank

9 January 2020

15952871

incorrect identifier value

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Fatcat

https://api.fatcat.wiki/v0/release/6nm7meumd5fttiybgm7up47iye

9 June 2023