Structure-function relationships in human testis-determining factor SRY: an aromatic buttress underlies the specific DNA-bending surface of a high mobility group (HMG) box. (Q34552512)

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English	Structure-function relationships in human testis-determining factor SRY: an aromatic buttress underlies the specific DNA-bending surface of a high mobility group (HMG) box.	scientific article

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Europe PubMed Central

PubMed publication ID

3 August 2017

Structure-function relationships in human testis-determining factor SRY: an aromatic buttress underlies the specific DNA-bending surface of a high mobility group (HMG) box. (English)

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Europe PubMed Central

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3 August 2017

Nalinda P Wickramasinghe

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258310%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

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Joseph D Racca

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3 June 2020

Yen-Shan Chen

2

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3 June 2020

James D Maloy

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3 June 2020

Nelson B Phillips

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Michael A Weiss

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24 September 2014

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3 August 2017

Journal of Biological Chemistry

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3 June 2020

289

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47

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Advantages of proteins being disordered.

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Interplay between conformational selection and induced fit in multidomain protein-ligand binding probed by paramagnetic relaxation enhancement.

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Inherited human sex reversal due to impaired nucleocytoplasmic trafficking of SRY defines a male transcriptional threshold

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SRY protein function in sex determination: thinking outside the box.

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Exportin 4 interacts with Sox9 through the HMG Box and inhibits the DNA binding of Sox9.

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Mammalian testis-determining factor SRY and the enigma of inherited human sex reversal: frustrated induced fit in a bent protein-DNA complex.

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Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations

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SRY: A transcriptional activator of mammalian testis determination

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A novel SRY missense mutation affecting nuclear import in a 46,XY female patient with bilateral gonadoblastoma.

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Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog

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The makings of maleness: towards an integrated view of male sexual development

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SRY-directed DNA bending and human sex reversal: reassessment of a clinical mutation uncovers a global coupling between the HMG box and its tail

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From stem cells to neurons and glia: a Soxist's view of neural development

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Sox genes and cancer

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Defective importin beta recognition and nuclear import of the sex-determining factor SRY are associated with XY sex-reversing mutations.

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A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination

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Sex-determining genes in mice: building pathways.

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A cavity-forming mutation in insulin induces segmental unfolding of a surrounding α-helix

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Structural basis for SRY-dependent 46-X,Y sex reversal: modulation of DNA bending by a naturally occurring point mutation

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Regulation of male sexual development by Sry and Sox9.

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The C-terminal nuclear localization signal of the sex-determining region Y (SRY) high mobility group domain mediates nuclear import through importin beta 1.

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SRYand architectural gene regulation: the kinetic stability of a bent protein-DNA complex can regulate its transcriptional potency

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Floppy SOX: mutual induced fit in hmg (high-mobility group) box-DNA recognition.

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Pairing SOX off: with partners in the regulation of embryonic development

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Regulation of sexual dimorphism in mammals

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The SRY cantilever motif discriminates between sequence- and structure-specific DNA recognition: alanine mutagenesis of an HMG box.

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Molecular basis of mammalian sexual determination: activation of Müllerian inhibiting substance gene expression by SRY.

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Male development of chromosomally female mice transgenic for Sry.

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A structural taxonomy of DNA-binding domains

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Human testis-determining factor SRY binds to the major DNA adduct of cisplatin and a putative target sequence with comparable affinities.

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Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

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21 January 2018

Sry-directed sex reversal in transgenic mice is robust with respect to enhanced DNA bending: comparison of human and murine HMG boxes

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Structural basis for the nuclear protein import cycle.

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21 January 2018

Inhibition of SRY-calmodulin complex formation induces ectopic expression of ovarian cell markers in developing XY gonads.

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21 January 2018

Alpha-lactalbumin forms a compact molten globule in the absence of disulfide bonds.

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Getting a grip on DNA recognition: structures of the basic region leucine zipper, and the basic region helix-loop-helix DNA-binding domains

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21 January 2018

The LEF-1 high-mobility group domain undergoes a disorder-to-order transition upon formation of a complex with cognate DNA.

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https://api.crossref.org/works/10.1074%2FJBC.M114.597526

21 January 2018

The Schizosaccharomyces pombe mating-type gene mat-Mc encodes a sequence-specific DNA-binding high mobility group box protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239596

27 October 2018

The energetics of HMG box interactions with DNA. Thermodynamic description of the box from mouse Sox-5 1 1Edited by P. E. Wright

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.597526

21 January 2018

Folding transition in the DMA-binding domain of GCN4 on specific binding to DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.597526

21 January 2018

Protein folding. Solid evidence for molten globules

1 reference

https://pubmed.ncbi.nlm.nih.gov/25258310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and subcellular localization of SF-1, SOX9, WT1, and AMH proteins during early human testicular development

1 reference

https://pubmed.ncbi.nlm.nih.gov/25258310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMGs everywhere

1 reference

https://pubmed.ncbi.nlm.nih.gov/25258310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The energetics of HMG box interactions with DNA: thermodynamics of the DNA binding of the HMG box from mouse sox-5

1 reference

https://pubmed.ncbi.nlm.nih.gov/25258310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective calmodulin-mediated nuclear transport of the sex-determining region of the Y chromosome (SRY) in XY sex reversal

1 reference

https://pubmed.ncbi.nlm.nih.gov/25258310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Filling a cavity dramatically increases pressure stability of the c-Myb R2 subdomain

1 reference

https://pubmed.ncbi.nlm.nih.gov/25258310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/25258310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.597526

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258310%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

release_pocq62ejr5cqrmb7el6gtfbkey

1 reference

https://api.fatcat.wiki/v0/release/pocq62ejr5cqrmb7el6gtfbkey

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258310%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258310%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

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