The breakage-fusion-bridge (BFB) cycle as a mechanism for generating genetic heterogeneity in osteosarcoma (Q34555501)

3 August 2017

title

The breakage-fusion-bridge (BFB) cycle as a mechanism for generating genetic heterogeneity in osteosarcoma (English)

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3 August 2017

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Jeremy A Squire

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author name string

Shamini Selvarajah

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Maisa Yoshimoto

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Paul C Park

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Georges Maire

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Jana Paderova

5

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Jane Bayani

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Gloria Lim

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Khaldoun Al-Romaih

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Maria Zielenska

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3 August 2017

publication date

9 August 2006

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3 August 2017

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3 August 2017

volume

115

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3 August 2017

issue

6

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3 August 2017

page(s)

459-467

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Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences

3 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00412-006-0074-4

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

21 January 2018

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12 December 2020

The Stability of Broken Ends of Chromosomes in Zea Mays.

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12 December 2020

Spectral karyotyping identifies recurrent complex rearrangements of chromosomes 8, 17, and 20 in osteosarcomas

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12 December 2020

Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture.

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12 December 2020

Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas

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12 December 2020

Centrosomal amplification and spindle multipolarity in cancer cells

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12 December 2020

Comparative genomic hybridization analysis identifies gains of 1p35∼p36 and chromosome 19 in osteosarcoma

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12 December 2020

Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells

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12 December 2020

An integrated mBAND and submegabase resolution tiling set (SMRT) CGH array analysis of focal amplification, microdeletions, and ladder structures consistent with breakage-fusion-bridge cycle events in osteosarcoma

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12 December 2020

High-resolution cDNA microarray CGH mapping of genomic imbalances in osteosarcoma using formalin-fixed paraffin-embedded tissue

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12 December 2020

Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus

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12 December 2020

Masquerading repeats: paralogous pitfalls of the human genome

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12 December 2020

Genetic instability and darwinian selection in tumours

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12 December 2020

Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma

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12 December 2020

Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity

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12 December 2020

Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification

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12 December 2020

Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice

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12 December 2020

Gene amplifications in osteosarcoma-CGH microarray analysis

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12 December 2020

When, where and how the bridge breaks: anaphase bridge breakage plays a crucial role in gene amplification and HSR generation

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12 December 2020

Variable stability of chromosomes containing amplified alpha-satellite sequences in human mesenchymal tumours

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12 December 2020

Combined spectral karyotyping, multicolor banding, and microarray comparative genomic hybridization analysis provides a detailed characterization of complex structural chromosomal rearrangements associated with gene amplification in the osteosarcoma

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12 December 2020

Cytogenetic studies on fine-needle aspiration samples from osteosarcoma and Ewing's sarcoma

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12 December 2020

Resolution of anaphase bridges in cancer cells

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12 December 2020

Chromosome instability in cancer: how, when, and why?

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12 December 2020

Chromosomal instability in osteosarcoma and its association with centrosome abnormalities

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12 December 2020

Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres

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12 December 2020

Chromosomal regions involved in the pathogenesis of osteosarcomas.

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12 December 2020

The role of chromosomal instability in tumor initiation

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12 December 2020

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

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12 December 2020

Can chromosomal instability initiate tumorigenesis?

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12 December 2020

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A

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12 December 2020

Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity

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12 December 2020

Mutator phenotype may be required for multistage carcinogenesis

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Chromosomal instability.

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12 December 2020

Centrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeres

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12 December 2020

Chromosomal translocations in sarcomas: prospects for therapy

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Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

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12 December 2020

Pathways of DNA double-strand break repair and their impact on the prevention and formation of chromosomal aberrations

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12 December 2020

Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization

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12 December 2020

Chromosomal instability and marker chromosome evolution in oral squamous cell carcinoma

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12 December 2020

High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use of CGH analysis of cDNA microarrays

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12 December 2020

Cytogenetic and fluorescence in situ hybridization characterization of chromosome 8 rearrangements in head and neck squamous cell carcinomas

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12 December 2020

Cytogenetic findings in 33 osteosarcomas

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12 December 2020

Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis

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12 December 2020

Mitotic instability associated with late genomic changes in bone and soft tissue tumours

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12 December 2020

10.1007/S00412-006-0074-4

Identifiers

DOI

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3 August 2017

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