Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses (Q34557323)

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English	Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses	scientific article

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scholarly article

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Europe PubMed Central

3 August 2017

Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses (English)

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Europe PubMed Central

3 August 2017

apoptotic process

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hypermethylation

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based on heuristic

inferred from title

author name string

Lee MG

1

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Europe PubMed Central

3 August 2017

Huh JS

2

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Europe PubMed Central

3 August 2017

Chung SK

3

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Europe PubMed Central

3 August 2017

Lee JH

4

1 reference

Europe PubMed Central

3 August 2017

Byun DS

5

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Europe PubMed Central

3 August 2017

Ryu BK

6

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Europe PubMed Central

3 August 2017

Kang MJ

7

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Europe PubMed Central

3 August 2017

Chae KS

8

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Europe PubMed Central

3 August 2017

Lee SJ

9

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Europe PubMed Central

3 August 2017

Lee CH

10

1 reference

Europe PubMed Central

3 August 2017

Kim JI

11

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3 August 2017

Chang SG

12

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3 August 2017

Chi SG

13

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3 August 2017

language of work or name

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publication date

7 August 2006

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3 August 2017

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3 August 2017

25

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3 August 2017

42

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3 August 2017

5807-5822

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Europe PubMed Central

3 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209867

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A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

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Intravesical Ad-IFNalpha causes marked regression of human bladder cancer growing orthotopically in nude mice and overcomes resistance to IFN-alpha protein

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Role of XIAP in the malignant phenotype of transitional cell cancer (TCC) and therapeutic activity of XIAP antisense oligonucleotides against multidrug-resistant TCC in vitro.

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p53 in prostate cancer: frequent expressed transition mutations

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IAP family proteins--suppressors of apoptosis

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X-linked IAP is a direct inhibitor of cell-death proteases

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines

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Apoptotic pathways: paper wraps stone blunts scissors

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XIAP: apoptotic brake and promising therapeutic target.

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Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis

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Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

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Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

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Tumor necrosis factor-related apoptosis-inducing ligand: a novel mechanism for Bacillus Calmette-Guérin-induced antitumor activity.

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XAF1 expression is significantly reduced in human melanoma

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Role of tumor necrosis factor-related apoptosis-inducing ligand in interferon-induced apoptosis in human bladder cancer cells

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Motoneuron resistance to apoptotic cell death in vivo correlates with the ratio between X-linked inhibitor of apoptosis proteins (XIAPs) and its inhibitor, XIAP-associated factor 1.

1 reference

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The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

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Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

1 reference

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NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

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Apoptosis in the pathogenesis and treatment of disease

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Alterations of the retinoblastoma gene in human prostate adenocarcinoma

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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Mutational abrogation of the PTEN/MMAC1 gene in gastrointestinal polyps in patients with Cowden disease

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Changes in urinary cytokines and soluble intercellular adhesion molecule-1 (ICAM-1) in bladder cancer patients after bacillus Calmette-Guérin (BCG) immunotherapy

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Expression of inhibitor of apoptosis proteins (IAPs) in rat granulosa cells during ovarian follicular development and atresia

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Induction and redistribution of XAF1, a new antagonist of XIAP in the rat brain after transient focal ischemia

1 reference

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Patterns of chromosomal aberrations in urinary bladder tumours and adjacent urothelium

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Identifiers

10.1038/SJ.ONC.1209867

1 reference

Europe PubMed Central

3 August 2017

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Europe PubMed Central

3 August 2017

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