Translating research into clinical scale manufacturing of mesenchymal stromal cells (Q34557484)

3 August 2017

1 reference

title

Translating research into clinical scale manufacturing of mesenchymal stromal cells (English)

1 reference

3 August 2017

Karen Bieback

1

1 reference

PubMed ID

21318154

3 August 2017

Sven Kinzebach

series ordinal

2

1 reference

PubMed ID

21318154

3 August 2017

Marianna Karagianni

series ordinal

3

1 reference

3 August 2017

20 January 2011

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3 August 2017

Stem Cells International

1 reference

3 August 2017

2010

1 reference

3 August 2017

193519

1 reference

Creative Commons Attribution 3.0 Unported

3 August 2017

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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7 July 2018

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Current Regulations for the Production of Multipotent Mesenchymal Stromal Cells for Clinical Application

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Trophic molecules derived from human mesenchymal stem cells enhance survival, function, and angiogenesis of isolated islets after transplantation

7 July 2018

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Comparative studies of different cryopreservation methods for mesenchymal stem cells derived from human fetal liver.

7 July 2018

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Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation

7 July 2018

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The effect of bone marrow aspiration strategy on the yield and quality of human mesenchymal stem cells

7 July 2018

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Cord blood banking for clinical transplantation

7 July 2018

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A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice

7 July 2018

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7 July 2018

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Cytokines as the major mechanism of mesenchymal stem cell clinical activity: expanding the spectrum of cell therapy

7 July 2018

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Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis

7 July 2018

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Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression

7 July 2018

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Mesenchymal stem cells: flip side of the coin

7 July 2018

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Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?

7 July 2018

1 reference

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Mesenchymal stem cells: revisiting history, concepts, and assays.

7 July 2018

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Effect of tissue-harvesting site on yield of stem cells derived from adipose tissue: implications for cell-based therapies

7 July 2018

1 reference

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Clinical grade production of mesenchymal stem cells

7 July 2018

1 reference

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Comparing mesenchymal stromal cells from different human tissues: bone marrow, adipose tissue and umbilical cord blood.

7 July 2018

1 reference

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Mesenchymal stromal cells from umbilical cord blood

7 July 2018

1 reference

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The anti-inflammatory and anti-angiogenic role of mesenchymal stem cells in corneal wound healing following chemical injury

7 July 2018

1 reference

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Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice

7 July 2018

1 reference

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Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells

7 July 2018

1 reference

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Cell-based therapy of myocardial infarction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair--current views

7 July 2018

1 reference

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Immune plasticity of bone marrow-derived mesenchymal stromal cells

7 July 2018

1 reference

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Mesenchymal stem cell features of Ewing tumors

7 July 2018

1 reference

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Concise review: no breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serum-free, serum replacement nonconditioned med

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Earlier onset of syngeneic tumors in the presence of mesenchymal stem cells

7 July 2018

1 reference

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Concise review: multipotent mesenchymal stromal cells in blood

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Mesenchymal stem cells as trophic mediators

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

The long journey from stem cells to medical product

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

The role of mesenchymal stem cells in haemopoiesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Aging of mesenchymal stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Human adipose tissue is a source of multipotent stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Mesenchymal stem-cell therapy in a regulated environment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Recovery of human mesenchymal stem cells following dehydration and rehydration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Multilineage potential of adult human mesenchymal stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Prospects for stem cell-based therapy.

7 July 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Isolation and production of cells suitable for human therapy: challenges ahead.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Stem cell therapies in clinical trials: workshop on best practices and the need for harmonization

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Altered gene expression in human adipose stem cells cultured with fetal bovine serum compared to human supplements

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Pitfalls in spontaneous in vitro transformation of human mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Challenges with advanced therapy medicinal products and how to meet them.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Impaired differentiation potential of human trabecular bone mesenchymal stromal cells from elderly patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Human platelet lysate allows expansion and clinical grade production of mesenchymal stromal cells from small samples of bone marrow aspirates or marrow filter washouts.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Isolation of human mesenchymal stromal cells is more efficient by red blood cell lysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Mesenchymal stem cell concentration and bone repair: potential pitfalls from bench to bedside.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Treatment of enterocutaneous fistula in Crohn's Disease with adipose-derived stem cells: a comparison of protocols with and without cell expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Human AB serum and thrombin-activated platelet-rich plasma are suitable alternatives to fetal calf serum for the expansion of mesenchymal stem cells from adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Bioreactor expansion of human adult bone marrow-derived mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Defining the risks of mesenchymal stromal cell therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Effect of holding time, temperature and different parenteral solutions on viability and functionality of adult bone marrow-derived mesenchymal stem cells before transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Potential risks of bone marrow cell transplantation into infarcted hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Suspension medium influences interaction of mesenchymal stromal cells with endothelium and pulmonary toxicity after transplantation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Human preadipocytes display a depot-specific susceptibility to apoptosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034974

Parameters in Three-Dimensional Osteospheroids of Telomerized Human Mesenchymal (Stromal) Stem Cells Grown on Osteoconductive Scaffolds That Predict In Vivo Bone-Forming Potential

27 October 2018

1 reference

https://api.crossref.org/works/10.4061%2F2010%2F193519

Differences in stem and progenitor cell yield in different subcutaneous adipose tissue depots

21 January 2018

1 reference

12 December 2020

HLA expression and immunologic propertiesof differentiated and undifferentiated mesenchymal stem cells

1 reference

12 December 2020

Endothelial Colony Forming Cells and Mesenchymal Stem Cells are Enriched at Different Gestational Ages in Human Umbilical Cord Blood

1 reference

12 December 2020

Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex

1 reference

12 December 2020

Comparison of pre-adipocyte yield, growth and differentiation characteristics from excised versus aspirated adipose tissue

1 reference

12 December 2020

Is the intravascular administration of mesenchymal stem cells safe? Mesenchymal stem cells and intravital microscopy

1 reference

12 December 2020

Good manufacturing practice-compliant expansion of marrow-derived stem and progenitor cells for cell therapy

1 reference

12 December 2020

Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy

1 reference

12 December 2020

The Bedside Celution system for isolation of adipose derived regenerative cells

1 reference

12 December 2020

Influence of negative pressure when harvesting adipose tissue on cell yield of the stromal-vascular fraction

1 reference

12 December 2020

Stem cell clinics online: the direct-to-consumer portrayal of stem cell medicine

1 reference

12 December 2020

Retention of multilineage differentiation potential of mesenchymal cells during proliferation in response to FGF

1 reference

12 December 2020

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter

1 reference

12 December 2020

Identifiers

DOI

10.4061/2010/193519

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

PubMed ID

21318154