Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling (Q34557811)

3 August 2017

title

Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling (English)

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3 August 2017

Yasunari Miyazaki

1

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3 August 2017

Adriana Vieira-de-Abreu

2

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3 August 2017

Estelle S Harris

3

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3 August 2017

Amrapali M Shah

4

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3 August 2017

Andrew S Weyrich

5

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3 August 2017

Hugo C Castro-Faria-Neto

6

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3 August 2017

Guy A Zimmerman

7

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3 August 2017

language of work or name

English

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publication date

21 November 2014

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3 August 2017

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3 August 2017

volume

9

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3 August 2017

issue

11

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3 August 2017

page(s)

e112770

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Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

21 November 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The role of integrin alpha D beta2 (CD11d/CD18) in monocyte/macrophage migration

7 July 2018

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Transient blockage of the CD11d/CD18 integrin reduces contusion volume and macrophage infiltration after traumatic brain injury in rats

7 July 2018

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Integrin alphaDbeta2 is dynamically expressed by inflamed macrophages and alters the natural history of lethal systemic infections

7 July 2018

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Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.

7 July 2018

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mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.

7 July 2018

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Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling

7 July 2018

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The inflammasome: first line of the immune response to cell stress

7 July 2018

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From the membrane to the nucleus and back again: bifunctional focal adhesion proteins

7 July 2018

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The many roles of chemokines and chemokine receptors in inflammation

7 July 2018

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Monocyte and macrophage heterogeneity

7 July 2018

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Integrin alphaDbeta2, an adhesion receptor up-regulated on macrophage foam cells, exhibits multiligand-binding properties

7 July 2018

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Estrogen selectively promotes the differentiation of dendritic cells with characteristics of Langerhans cells

7 July 2018

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Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates

7 July 2018

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The leukocyte integrin gene CD11d is repressed by gut-enriched Kruppel-like factor 4 in myeloid cells

7 July 2018

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Activated polymorphonuclear leukocytes rapidly synthesize retinoic acid receptor-alpha: a mechanism for translational control of transcriptional events.

7 July 2018

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Deficiency of CD11b or CD11d results in reduced staphylococcal enterotoxin-induced T cell response and T cell phenotypic changes

7 July 2018

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Neutrophils alter the inflammatory milieu by signal-dependent translation of constitutive messenger RNAs.

7 July 2018

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7 July 2018

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Cell-cell interactions: leukocyte-endothelial interactions

7 July 2018

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Expression of the myeloid-specific leukocyte integrin gene CD11d during macrophage foam cell differentiation and exposure to lipoproteins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome

7 July 2018

1 reference

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Integrins: bidirectional, allosteric signaling machines

7 July 2018

1 reference

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Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes

7 July 2018

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Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis

7 July 2018

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7 July 2018

The leukocyte integrins

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Structural and functional characterization of the leukocyte integrin gene CD11d. Essential role of Sp1 and Sp3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Of man and mouse: leukocyte and endothelial adhesion molecule deficiencies.

7 July 2018

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The leukocyte integrin alpha D beta 2 binds VCAM-1: evidence for a binding interface between I domain and VCAM-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

alphadbeta2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM-1)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

A novel leukointegrin, alpha d beta 2, binds preferentially to ICAM-3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Signal transduction from the extracellular matrix

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Ligation of platelet/endothelial cell adhesion molecule 1 (PECAM-1/CD31) on monocytes and neutrophils increases binding capacity of leukocyte CR3 (CD11b/CD18).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Cytoskeletal control of gene expression: depolymerization of microtubules activates NF-kappa B

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Activation of lymphocyte function-associated molecule-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) mimicked by an antibody directed against CD18

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Human monocytes CD36 and CD16 are signaling molecules. Evidence from studies using antibody-induced chemiluminescence as a tool to probe signal transduction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats.

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0112770

Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0112770

Estradiol attenuates lipopolysaccharide-induced CXC chemokine ligand 8 production by human peripheral blood monocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0112770

A role for beta(2) integrins (CD11/CD18) in the regulation of cytokine gene expression of polymorphonuclear neutrophils during the inflammatory response.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Coengagement of ICAM-3 and Fc receptors induces chemokine secretion and spreading by myeloid leukocytes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

A novel canine leukointegrin, alpha d beta 2, is expressed by specific macrophage subpopulations in tissue and a minor CD8+ lymphocyte subpopulation in peripheral blood

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Ligation of L-selectin through conserved regions within the lectin domain activates signal transduction pathways and integrin function in human, mouse, and rat leukocytes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240710

Synovial distribution of αd/CD18, a novel leukointegrin. Comparison with other integrins and their ligands

27 October 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0112770

Dendritic cells as the terminal stage of monocyte differentiation

21 January 2018

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12 December 2020

The extracellular domain of CD11d regulates its cell surface expression

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12 December 2020

Selective mobilization of CD14(+)CD16(+) monocytes by exercise

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12 December 2020

Requirements for alpha d in IgG immune complex-induced rat lung injury

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12 December 2020

Platelet-activating factor acetylhydrolase increases during macrophage differentiation. A novel mechanism that regulates accumulation of platelet-activating factor

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12 December 2020

Engagement of CD11b and CD11c beta2 integrin by antibodies or soluble CD23 induces IL-1beta production on primary human monocytes through mitogen-activated protein kinase-dependent pathways

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12 December 2020

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12 December 2020

The acute respiratory distress syndrome

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12 December 2020

LAD syndromes: FERMT3 kindles the signal

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12 December 2020

Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women

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12 December 2020

A monoclonal antibody to CD11d reduces the inflammatory infiltrate into the injured spinal cord: a potential neuroprotective treatment

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12 December 2020

Adherence induces selective mRNA expression of monocyte mediators and proto-oncogenes

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12 December 2020

10.1371/JOURNAL.PONE.0112770

Identifiers

DOI

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3 August 2017

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3 August 2017

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