Decreased CD4 expression by polarized T helper 2 cells contributes to suboptimal TCR-induced phosphorylation and reduced Ca2+ signaling (Q34562425)

3 August 2017

title

Decreased CD4 expression by polarized T helper 2 cells contributes to suboptimal TCR-induced phosphorylation and reduced Ca2+ signaling (English)

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3 August 2017

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8

Ronald N Germain

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3 August 2017

Yasushi Itoh

1

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3 August 2017

Ze Wang

2

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3 August 2017

Hideaki Ishida

3

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3 August 2017

Katrin Eichelberg

4

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3 August 2017

Noriki Fujimoto

5

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3 August 2017

Jin Makino

6

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3 August 2017

Kazumasa Ogasawara

7

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3 August 2017

language of work or name

English

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publication date

1 November 2005

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European Journal of Immunology

3 August 2017

published in

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3 August 2017

volume

35

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3 August 2017

issue

11

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3 August 2017

page(s)

3187-3195

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Is selection for TCR affinity a factor in cytokine polarization?

3 August 2017

cites work

1 reference

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Early events of TCR signaling are distinct in human Th1 and Th2 cells

7 July 2018

1 reference

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T cell receptor signaling precedes immunological synapse formation

7 July 2018

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Differential clustering of CD4 and CD3zeta during T cell recognition

7 July 2018

1 reference

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Signaling and transcription in T helper development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Transcript imaging of the development of human T helper cells using oligonucleotide arrays

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Regulation of naive T cell differentiation by varying the potency of TCR signal transduction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype.

7 July 2018

1 reference

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The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands

7 July 2018

1 reference

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Deficient expression of p56(lck) in Th2 cells leads to partial TCR signaling and a dysregulation in lymphokine mRNA levels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists

7 July 2018

1 reference

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A common factor regulates both Th1- and Th2-specific cytokine gene expression

7 July 2018

1 reference

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The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

7 July 2018

1 reference

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Th2 cell clonal anergy as a consequence of partial activation

7 July 2018

1 reference

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Acquisition of lymphokine-producing phenotype by CD4+ T cells

7 July 2018

1 reference

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Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Heterogeneity of cytokine secretion patterns and functions of helper T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

7 July 2018

1 reference

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The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Isolation of self antigen-reactive cells from inflamed islets of nonobese diabetic mice using CD4high expression as a marker.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Relationships among TCR ligand potency, thresholds for effector function elicitation, and the quality of early signaling events in human T cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459334

Difference in signal transduction pathway for IL-2 and IL-4 production in T helper 1 and T helper 2 cell clones in response to anti-CD3

27 October 2018

1 reference

12 December 2020

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

1 reference

12 December 2020

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

1 reference

12 December 2020

Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

1 reference

12 December 2020

Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones

1 reference

12 December 2020

Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: relationship to the quality of individual TCR signaling events

1 reference

12 December 2020

Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene

1 reference

12 December 2020

Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells

1 reference

12 December 2020

Early activation signal transduction pathways of Th1 and Th2 cell clones stimulated with anti-CD3. Roles of protein tyrosine kinases in the signal for IL-2 and IL-4 production

1 reference

12 December 2020

Identifiers

DOI

10.1002/EJI.200526064

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3 August 2017

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3 August 2017

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