Palmitoylethanolamide normalizes intestinal motility in a model of post-inflammatory accelerated transit: involvement of CB₁ receptors and TRPV1 channels (Q34571380)

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English	Palmitoylethanolamide normalizes intestinal motility in a model of post-inflammatory accelerated transit: involvement of CB₁ receptors and TRPV1 channels	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Palmitoylethanolamide normalizes intestinal motility in a model of post-inflammatory accelerated transit: involvement of CB₁ receptors and TRPV1 channels (English)

1 reference

Europe PubMed Central

3 August 2017

object named as

Lorena Buono

5

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object named as

Ester Pagano

3

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Raffaele Capasso

object named as

Raffaele Capasso

1

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object named as

Angelo A Izzo

8

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Vincenzo Di Marzo

object named as

Vincenzo Di Marzo

7

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author name string

Pierangelo Orlando

2

1 reference

Europe PubMed Central

3 August 2017

Teresa Aveta

4

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Europe PubMed Central

3 August 2017

Francesca Borrelli

6

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Europe PubMed Central

3 August 2017

language of work or name

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publication date

1 September 2014

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Europe PubMed Central

3 August 2017

British Journal of Pharmacology

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Europe PubMed Central

3 August 2017

171

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Europe PubMed Central

3 August 2017

17

1 reference

Europe PubMed Central

3 August 2017

4026-4037

1 reference

Europe PubMed Central

3 August 2017

The Concise Guide to PHARMACOLOGY 2013/14: ion channels

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The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors

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7 July 2018

Endocannabinoid and cannabinoid-like fatty acid amide levels correlate with pain-related symptoms in patients with IBS-D and IBS-C: a pilot study

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7 July 2018

A role for PPARα in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats

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7 July 2018

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

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7 July 2018

Palmitoylethanolamide, a naturally occurring disease-modifying agent in neuropathic pain.

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7 July 2018

Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease

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7 July 2018

Measurement of palmitoylethanolamide and other N-acylethanolamines during physiological and pathological conditions.

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7 July 2018

Palmitoylethanolamide in homeostatic and traumatic central nervous system injuries

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Drug development for the irritable bowel syndrome: current challenges and future perspectives

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7 July 2018

The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis

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7 July 2018

Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy

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7 July 2018

Peripheral mechanisms in irritable bowel syndrome

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7 July 2018

Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Treatment of irritable bowel syndrome: sex and gender specific aspects

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7 July 2018

Brain-Gut Interactions in IBS

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Modulation of gastrointestinal function by MuDelta, a mixed µ opioid receptor agonist/ µ opioid receptor antagonist

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Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α.

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Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice.

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A role for neuropeptide Y in the gender-specific gastrointestinal, corticosterone and feeding responses to stress

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Herbal medicines for the management of irritable bowel syndrome: a comprehensive review

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7 July 2018

Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice

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7 July 2018

Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity.

1 reference

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7 July 2018

Small intestinal cannabinoid receptor changes following a single colonic insult with oil of mustard in mice

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7 July 2018

Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system

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7 July 2018

Complementary and alternative medicine for the irritable bowel syndrome

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7 July 2018

TRP channels in neurogastroenterology: opportunities for therapeutic intervention

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7 July 2018

Animal research: reporting in vivo experiments: the ARRIVE guidelines

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Guidelines for reporting experiments involving animals: the ARRIVE guidelines

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7 July 2018

The cannabinoid antagonist SR144528 enhances the acute effect of WIN 55,212-2 on gastrointestinal motility in the rat.

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7 July 2018

Cannabinoid activation of peroxisome proliferator-activated receptors: potential for modulation of inflammatory disease.

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7 July 2018

The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis

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7 July 2018

Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

The role of the endocannabinoid system in the pathophysiology and treatment of irritable bowel syndrome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain

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7 July 2018

The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet

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7 July 2018

The N-acylethanolamine-hydrolyzing acid amidase (NAAA).

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7 July 2018

Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine

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7 July 2018

Cannabinoids and the Digestive Tract

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

https://pubmed.ncbi.nlm.nih.gov/24818658

12 December 2020

based on heuristic

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Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: review of the available pre-clinical data, and first human studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Infection, immune function, and functional gut disorders

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

'Entourage' effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells

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7 July 2018

Effect of vanilloid drugs on gastrointestinal transit in mice

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7 July 2018

The palmitoylethanolamide and oleamide enigmas : are these two fatty acid amides cannabimimetic?

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7 July 2018

Control of pain initiation by endogenous cannabinoids.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

7 July 2018

Novel insights which may translate into treatments for irritable bowel syndrome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

Palmitoylethanolamide improves colon inflammation through an enteric glia/toll like receptor 4-dependent PPAR-α activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

Decreased enteric fatty acid amide hydrolase activity is associated with colonic inertia in slow transit constipation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-alpha ligands in Zucker rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

The identification of peroxisome proliferator-activated receptor alpha-independent effects of oleoylethanolamide on intestinal transit in mice

1 reference

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27 October 2018

Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

Acute colitis induction by oil of mustard results in later development of an IBS-like accelerated upper GI transit in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

Attenuation of nerve growth factor-induced visceral hyperalgesia via cannabinoid CB(1) and CB(2)-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

A new model of visceral pain and referred hyperalgesia in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243976

27 October 2018

Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24818658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of intestinal motility by anandamide, an endogenous cannabinoid

1 reference

https://pubmed.ncbi.nlm.nih.gov/24818658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute Intracerebroventricular Administration of Palmitoylethanolamide, an Endogenous Peroxisome Proliferator-Activated Receptor- Agonist, Modulates Carrageenan-Induced Paw Edema in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24818658

12 December 2020

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Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24818658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1111/BPH.12759

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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