Inhibitor-binding mode of homobelactosin C to proteasomes: new insights into class I MHC ligand generation (Q34574839)

3 August 2017

title

Inhibitor-binding mode of homobelactosin C to proteasomes: new insights into class I MHC ligand generation (English)

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Proteasome core particle subunit alpha 2 YML092C

3 August 2017

main subject

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Proteasome core particle subunit beta 5 YPR103W

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Proteasome core particle subunit alpha 1 YGL011C

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Proteasome core particle subunit alpha 7 YOR362C

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3

Robert Huber

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3 August 2017

Michael Groll

1

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3 August 2017

Oleg V Larionov

series ordinal

2

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3 August 2017

Armin de Meijere

series ordinal

4

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3 August 2017

language of work or name

English

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publication date

13 March 2006

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

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3 August 2017

volume

103

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3 August 2017

issue

12

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3 August 2017

page(s)

4576-4579

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Molecular machines for protein degradation

3 August 2017

cites work

1 reference

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Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach

7 July 2018

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Enantioselective total syntheses of belactosin A, belactosin C, and its homoanalogue

7 July 2018

1 reference

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Multiparametric scaling of diffraction intensities

7 July 2018

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The structure of the mammalian 20S proteasome at 2.75 A resolution

7 July 2018

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The nature of the MHC class I peptide loading complex

7 July 2018

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The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study

7 July 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 July 2018

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Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

7 July 2018

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The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing

7 July 2018

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Structure of 20S proteasome from yeast at 2.4 A resolution

7 July 2018

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Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

7 July 2018

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20 S proteasomes are assembled via distinct precursor complexes. Processing of LMP2 and LMP7 proproteins takes place in 13-16 S preproteasome complexes

7 July 2018

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Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes

7 July 2018

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Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

7 July 2018

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LMP2+ proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes.

7 July 2018

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Structure of peptides associated with MHC class I molecules.

7 July 2018

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A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

7 July 2018

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Reconstitution by MHC-restricted peptides of HLA-A2 heavy chain with beta 2-microglobulin, in vitro

7 July 2018

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Subunit of the '20S' proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex

7 July 2018

1 reference

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A new structural class of proteasome inhibitors identified by microbial screening using yeast-based assay

7 July 2018

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Conformational constraints for protein self-cleavage in the proteasome

27 October 2018

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Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

27 October 2018

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Belactosin A, a novel antitumor antibiotic acting on cyclin/CDK mediated cell cycle regulation, produced by Streptomyces sp

27 October 2018

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12 December 2020

Purification, crystallization, and X-ray analysis of the yeast 20S proteasome

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

On the active site of proteases. 3. Mapping the active site of papain; specific peptide inhibitors of papain

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12 December 2020

MHC class I expression in mice lacking the proteasome subunit LMP-7

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12 December 2020

Interferon-gamma induces different subunit organizations and functional diversity of proteasomes

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12 December 2020

MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

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12 December 2020

A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0600647103

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3 August 2017

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3 August 2017

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