A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation (Q34579880)

3 August 2017

title

A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation (English)

1 reference

3 August 2017

1 reference

K A Siminovitch

1

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3 August 2017

V Misener

2

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3 August 2017

P C Kwong

3

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3 August 2017

Q L Song

4

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3 August 2017

P P Chen

5

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3 August 2017

language of work or name

English

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publication date

1 November 1989

1 reference

Journal of Clinical Investigation

3 August 2017

published in

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3 August 2017

volume

84

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3 August 2017

issue

5

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3 August 2017

page(s)

1675-1678

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A comprehensive set of sequence analysis programs for the VAX

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=304036

Anti-DNA autoantibody-producing hybridomas of normal human lymphoid cell origin

7 July 2018

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Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup

7 July 2018

1 reference

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Somatic generation of antibody diversity

7 July 2018

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Complete amino acid sequence of variable domains from two monoclonal human anti-gamma globulins of the Wa cross-idiotypic group: suggestion that the J segments are involved in the structural correlate of the idiotype

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=304036

Molecular cloning of a human immunoglobulin λ chain variable sequence

7 July 2018

1 reference

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The isolation of a human Ig Vλ gene from a recombinant library of chromosome 22 and estimation of its copy number

7 July 2018

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Antigenic specificities related to the cold agglutinin activity of gamma M globulins

7 July 2018

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Anti-human immunoglobulin G activity of membrane-bound monoclonal immunoglobulin M in lymphoproliferative disorders

7 July 2018

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Human retinoblastoma susceptibility gene: cloning, identification, and sequence

7 July 2018

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Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus

7 July 2018

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Evolutionary and somatic selection of the antibody repertoire in the mouse.

7 July 2018

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Evolution of antibody variable region structure during the immune response

7 July 2018

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A 16/6 idiotype-positive anti-DNA antibody is encoded by a conserved VH gene with no somatic mutation

7 July 2018

1 reference

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Cross-reacting idiotypes on cryoprecipitating rheumatoid factor

7 July 2018

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Somatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 mice

7 July 2018

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Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy

7 July 2018

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Early restriction of the human antibody repertoire

7 July 2018

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Relationship of human variable region heavy chain germ-line genes to genes encoding anti-DNA autoantibodies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=304036

Isolation and characterization of human VkIII germ-line genes. Implications for the molecular basis of human VkIII light chain diversity

7 July 2018

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Origin and diversification of anti-DNA antibodies

7 July 2018

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V genes encoding autoantibodies: molecular and phenotypic characteristics

7 July 2018

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Analysis of variable region genes encoding a human anti-DNA antibody of normal origin. Implications for the molecular basis of human autoimmune responses.

7 July 2018

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Activation of an excluded immunoglobulin allele in a human B lymphoma cell line

7 July 2018

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VH sequence of a human anti-Sm autoantibody. Evidence that autoantibodies can be unmutated copies of germline genes

7 July 2018

1 reference

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Complete amino acid sequence of the variable domains of two human IgM anti-gamma globulins (Lay/Pom) with shared idiotypic specificities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=304036

DNA sequencing with chain-terminating inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=304036

The role of clonal selection and somatic mutation in autoimmunity

7 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/2509520

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Idiotypic analyses of anti-DNA antibodies in systemic lupus and monoclonal gammopathy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/2509520

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/2509520

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI114347

1 reference

3 August 2017

1 reference

3 August 2017

1 reference