Constitutive CCND1/CDK2 activity substitutes for p53 loss, or MYC or oncogenic RAS expression in the transformation of human mammary epithelial cells (Q34579889)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Constitutive CCND1/CDK2 activity substitutes for p53 loss, or MYC or oncogenic RAS expression in the transformation of human mammary epithelial cells	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

3 August 2017

Constitutive CCND1/CDK2 activity substitutes for p53 loss, or MYC or oncogenic RAS expression in the transformation of human mammary epithelial cells (English)

1 reference

Europe PubMed Central

3 August 2017

author name string

Damian J Junk

1

1 reference

Europe PubMed Central

3 August 2017

Rocky Cipriano

2

1 reference

Europe PubMed Central

3 August 2017

Martha Stampfer

3

1 reference

Europe PubMed Central

3 August 2017

Mark W Jackson

4

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

4 February 2013

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

8

1 reference

Europe PubMed Central

3 August 2017

2

1 reference

Europe PubMed Central

3 August 2017

e53776

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

4 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Hallmarks of Cancer: The Next Generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Tipping the balance: Cdk2 enables Myc to suppress senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

A novel class of cyclin-dependent kinase inhibitors identified by molecular docking act through a unique mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

p53-mediated growth suppression in response to Nutlin-3 in cyclin D1 transformed cells occurs independently of p21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Molecular targets and anticancer potential of indole-3-carbinol and its derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Cyclin-dependent kinase inhibitors: novel anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

CDK inhibition and cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Induction of cyclin D1 overexpression by activated ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

7 July 2018

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053776

21 January 2018

Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053776

21 January 2018

In situ analyses of genome instability in breast cancer

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053776

21 January 2018

Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053776

21 January 2018

Cyclin D1 and prognosis in human breast cancer

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053776

21 January 2018

p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053776

21 January 2018

Relating genotype and phenotype in breast cancer: an analysis of the prognostic significance of amplification at eight different genes or loci and of p53 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563539

27 October 2018

Cyclin D1 protein expression and function in human breast cancer

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053776

21 January 2018

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining

1 reference

https://pubmed.ncbi.nlm.nih.gov/23390492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic relevance of gene amplifications and coamplifications in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23390492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth of normal human mammary cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/23390492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species- and cell type-specific requirements for cellular transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23390492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23390492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and amplification of cyclin genes in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23390492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0053776

1 reference

Europe PubMed Central

3 August 2017

2013PLoSO...853776J

0 references

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34579889&oldid=1865670110"