4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans (Q34580565)

3 August 2017

1 reference

title

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans (English)

1 reference

3 August 2017

1

Ulf Diczfalusy

1 reference

3 August 2017

4

Leif Bertilsson

1 reference

3 August 2017

Hanna Nylén

2

1 reference

PubMed ID

21219398

3 August 2017

Pontus Elander

series ordinal

3

1 reference

PubMed ID

21219398

3 August 2017

language of work or name

English

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publication date

1 February 2011

1 reference

3 August 2017

7

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British Journal of Clinical Pharmacology

inferred from page(s)

published in

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3 August 2017

71

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3 August 2017

2

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3 August 2017

183-189

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Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040538

Urinary 6?-hydroxycortisol: a validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040538

Metabolism of 4 beta -hydroxycholesterol in humans.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040538

Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040538

Oxysterol biosynthetic enzymes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040538

Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.

7 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

Plasma 4beta-hydroxycholesterol: an endogenous CYP3A metric?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

Cytochrome P450 induction by rifampicin in healthy subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 marker 4beta-hydroxycholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

CYP3A induction and inhibition by different antiretroviral regimens reflected by changes in plasma 4beta-hydroxycholesterol levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

In vivo comparisons of constitutive cytochrome P450 3A activity assessed by alprazolam, triazolam, and midazolam

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

Does the long plasma half-life of 4beta-hydroxycholesterol impact its utility as a cytochrome P450 3A (CYP3A) metric?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040538

Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians

27 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

Effect of SLCO1B1 polymorphism on induction of CYP3A4 by rifampicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

Effect of age and gender on tirilazad pharmacokinetics in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03773.X

The oxysterols cholest-5-ene-3 beta,4 alpha-diol, cholest-5-ene-3 beta,4 beta-diol and cholestane-3 beta,5 alpha,6 alpha-triol are formed during in vitro oxidation of low density lipoprotein, and are present in human atherosclerotic plaques

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040538

Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040538

Autoinduction of carbamazepine metabolism in children examined by a stable isotope technique

9 December 2018

1 reference

12 December 2020

On the mechanism of oxidation of cholesterol at C-7 in a lipoxygenase system

1 reference

12 December 2020

Use of an 18O2 inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in rat. Evidence for in vivo formation of 7-oxo-, 7 beta-hydroxy-, 24-hydroxy-, and 25-hydroxycholesterol

1 reference

12 December 2020

Identification and quantitation of cholest-5-ene-3 beta,4 beta-diol in rat liver and human plasma

1 reference

12 December 2020

CYP3A genetics in drug metabolism

1 reference

12 December 2020

10.1111/J.1365-2125.2010.03773.X

Identifiers

DOI

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

PubMed ID

21219398