Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism. (Q34584417)

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9 January 2020

title

Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism (English)

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9 January 2020

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M Flint Beal

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9 January 2020

author name string

Lichuan Yang

2

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9 January 2020

Beverly Lorenzo

3

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9 January 2020

Noel Y Calingasan

4

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9 January 2020

Andrew Schomer

5

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Anthony Sireci

6

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Elizabeth J Wille

7

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language of work or name

English

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publication date

31 October 2007

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Journal of Neurochemistry

9 January 2020

number of pages

9

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inferred from page(s)

published in

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volume

104

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issue

6

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9 January 2020

page(s)

1613-1621

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Kynurenine pathway measurements in Huntington's disease striatum: evidence for reduced formation of kynurenic acid

9 January 2020

cites work

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Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice.

21 January 2018

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Experimental models of Parkinson's disease

21 January 2018

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Mitochondrial dysfunction and oxidative damage in Alzheimer's and Parkinson's diseases and coenzyme Q10 as a potential treatment

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Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

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Biochemical, physiological and medical aspects of ubiquinone function

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Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration

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Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

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Antioxidant treatment of patients with Friedreich ataxia: four-year follow-up

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Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease

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Attenuation of cocaine and methamphetamine neurotoxicity by coenzyme Q10.

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A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS.

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Cofactor treatment improves ATP synthetic capacity in patients with oxidative phosphorylation disorders

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Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects

21 January 2018

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Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

21 January 2018

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Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10.

21 January 2018

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Effect of coenzyme Q(10) on biochemical and morphological changes in experimental ischemia in the rat brain.

21 January 2018

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Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property.

21 January 2018

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MPTP as a mitochondrial neurotoxic model of Parkinson's disease

21 January 2018

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Neurochemical findings in the MPTP model of Parkinson's disease

21 January 2018

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Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects.

21 January 2018

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Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

21 January 2018

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Redox status of plasma coenzyme Q10 indicates elevated systemic oxidative stress in Parkinson's disease.

21 January 2018

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Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10.

21 January 2018

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Metabolism and function of coenzyme Q.

21 January 2018

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Three classes of ubiquinone analogs regulate the mitochondrial permeability transition pore through a common site

21 January 2018

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Unbiased stereological estimation of the number of neurons in the human hippocampus.

21 January 2018

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Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients

21 January 2018

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A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities

21 January 2018

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Evaluation of the dietary effects of coenzyme Q in vivo by the oxidative stress marker, hydroxyoctadecadienoic acid and its stereoisomer ratio.

21 January 2018

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Coenzyme Q is an obligatory cofactor for uncoupling protein function

21 January 2018

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