Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis. (Q34589433)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190145%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis (English)

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19 January 2020

Treponema pallidum

1 reference

1 reference

Glaber Arturo Centurion Lara

7

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19 January 2020

8

Sheila A Lukehart

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19 January 2020

2

Barbara J Molini

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19 January 2020

author name string

Lorenzo Giacani

1

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19 January 2020

Eric Y Kim

3

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19 January 2020

B Charmie Godornes

4

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19 January 2020

B Troy Leader

5

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19 January 2020

Lauren C Tantalo

6

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19 January 2020

language of work or name

English

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publication date

26 February 2010

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19 January 2020

published in

Journal of Immunology

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19 January 2020

volume

184

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19 January 2020

issue

7

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19 January 2020

page(s)

3822-3829

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Quantitation of rabbit cytokine mRNA by real-time RT-PCR.

19 January 2020

cites work

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Antigenic variation of TprK V regions abrogates specific antibody binding in syphilis

7 July 2018

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Gene organization and transcriptional analysis of the tprJ, tprI, tprG, and tprF loci in Treponema pallidum strains Nichols and Sea 81-4.

7 July 2018

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Tpr homologs in Treponema paraluiscuniculi Cuniculi A strain.

7 July 2018

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Gene conversion: a mechanism for generation of heterogeneity in the tprK gene of Treponema pallidum during infection

7 July 2018

1 reference

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Sequence diversity of Treponema pallidum subsp. pallidum tprK in human syphilis lesions and rabbit-propagated isolates.

7 July 2018

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Protection against Syphilis Correlates with Specificity of Antibodies to the Variable Regions ofTreponema pallidumRepeat Protein K

7 July 2018

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Antigenic variation of Anaplasma marginale by expression of MSP2 mosaics

7 July 2018

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The tprK gene is heterogeneous among Treponema pallidum strains and has multiple alleles

7 July 2018

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Genetic variation of the Borrelia burgdorferi gene vlsE involves cassette-specific, segmental gene conversion

7 July 2018

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Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes

7 July 2018

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Surface characterization of virulent Treponema pallidum

7 July 2018

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Intracellular location of Treponema pallidum (Nichols strain) in the rabbit testis.

7 July 2018

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An electron microscopic study of a syphilitic chancre. Engulfment of Treponema pallidum by plasma cells

7 July 2018

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Treponema pallidum within cells of a primary chancre from a human female

7 July 2018

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Reinfection of chancre-immune rabbits with Treponema pallidum. I. Light and immunofluorescence studies

7 July 2018

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Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity

7 July 2018

1 reference

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Outer membrane ultrastructure explains the limited antigenicity of virulent Treponema pallidum

7 July 2018

1 reference

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Antigenic variation of a relapsing fever Borrelia species

7 July 2018

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Analysis of outer membrane ultrastructure of pathogenic Treponema and Borrelia species by freeze-fracture electron microscopy

7 July 2018

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A subpopulation of Treponema pallidum is resistant to phagocytosis: possible mechanism of persistence

7 July 2018

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Demonstration of the in vitro phagocytosis of Treponema pallidum by rabbit peritoneal macrophages

7 July 2018

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In vitro cell response of Treponema pallidum-infected rabbits. III. Impairment in production of lymphocyte mitogenic factor

7 July 2018

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Surface Mucopolysaccharides of Treponema pallidum

7 July 2018

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Quantitative analysis of tpr gene expression in Treponema pallidum isolates: Differences among isolates and correlation with T-cell responsiveness in experimental syphilis

7 July 2018

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TprK sequence diversity accumulates during infection of rabbits with Treponema pallidum subsp. pallidum Nichols strain

27 October 2018

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Treponema pallidum strain-specific differences in neuroinvasion and clinical phenotype in a rabbit model

27 October 2018

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Biology of the treponematoses based on studies carried out at the International Treponematosis Laboratory Center of the Johns Hopkins University under the auspices of the World Health Organization.

27 October 2018

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The immunoprotective niche— A new pathogenic mechanism for syphilis, the systemic mycoses and other infectious diseases

27 October 2018

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12 December 2020

In vitro cell response of Treponema pallidum-infected rabbits. II. Inhibition of lymphocyte response to phytohaemagglutinin by serum of T. pallidum-infected rabbits

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12 December 2020

Macrophage-Mediated Killing of Opsonized Treponema pallidum

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12 December 2020

Protective layer covering pathogenic treponemata

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12 December 2020

The Oslo study of untreated syphilis; an epidemiologic investigation of the natural course of the syphilitic infection based upon a re-study of the Boeck-Bruusgaard material

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12 December 2020

Segregation of B and T cell epitopes of Treponema pallidum repeat protein K to variable and conserved regions during experimental syphilis infection

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0902788

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190145%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

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19 January 2020

PubMed publication ID

20190145

1 reference