Glutamate receptor genes: susceptibility factors in schizophrenia and depressive disorders? (Q34590422)

3 August 2017

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title

Glutamate receptor genes: susceptibility factors in schizophrenia and depressive disorders? (English)

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3 August 2017

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Hans H Schiffer

1

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3 August 2017

1 April 2002

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3 August 2017

Molecular Neurobiology

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3 August 2017

25

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3 August 2017

2

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3 August 2017

191-212

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https://scigraph.springernature.com/pub.10.1385/mn:25:2:191

3 August 2017

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cites work

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Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

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Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

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Genomic imprinting in the brain

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Lithium modulates desensitization of the glutamate receptor subtype gluR3 in Xenopus oocytes.

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Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease

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Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo

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NMDA receptor subunits: diversity, development and disease

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PDZ protein interactions regulating glutamate receptor function and plasticity

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Neuronal apoptosis after CNS injury: the roles of glutamate and calcium.

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12 December 2020

The glutamate receptor ion channels

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12 December 2020

Direct microdissection and microcloning of a translocation breakpoint region, t(1;11)(q42.2;q21), associated with schizophrenia.

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12 December 2020

The effect of 1-arylcylohexylamine (sernyl) on twelve normal volunteers.

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12 December 2020

Chromosomal localization of the epsilon 1, epsilon 3 and zeta 1 subunit genes of the human NMDA receptor channel

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12 December 2020

Exclusion of linkage of schizophrenia of the gene for the glutamate GluR5 receptor

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12 December 2020

Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia

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12 December 2020

Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders

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12 December 2020

Efficacy and tolerance of D-cycloserine in drug-free schizophrenic patients

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12 December 2020

Epigenetic modification and imprinting of the mammalian genome during development.

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12 December 2020

The role of dopamine and AMPA/kainate receptors in the nucleus accumbens in the hypermotility response to MK801

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12 December 2020

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

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12 December 2020

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

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12 December 2020

Glutamate receptors in the postmortem striatum of schizophrenic, suicide, and control brains.

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12 December 2020

Phencyclidine-induced stereotyped behavior in monkeys: Antagonism by pimozide

1 reference

12 December 2020

Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.

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12 December 2020

Coordinate regulation of metabotropic glutamate receptors

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12 December 2020

Determination of membrane topology of glutamate receptors

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12 December 2020

The tetrameric structure of a glutamate receptor channel

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12 December 2020

Genomic cloning and localization by FISH and linkage analysis of the human gene encoding the primary subunit NMDAR1 (GRIN1) of the NMDA receptor channel

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12 December 2020

NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders

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12 December 2020

Studies on the distinction between uptake inhibition and release of [3H]dopamine in rat brain tissue slices

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12 December 2020

Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine

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12 December 2020

Co-localization of the D1 dopamine receptor in a subset of DARPP-32-containing neurons in rat caudate-putamen.

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12 December 2020

Molecular genetics of bipolar disorder.

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12 December 2020

Psychosis: pathological activation of limbic thalamocortical circuits by psychomimetics and schizophrenia?

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12 December 2020

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

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12 December 2020

Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method

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12 December 2020

Glycine agonists: what can they teach us about schizophrenia?

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12 December 2020

Neuroadaptations involved in amphetamine and cocaine addiction.

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12 December 2020

Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slices.

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12 December 2020

Subtype-specific effects of lithium on glutamate receptor function

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12 December 2020

The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis

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12 December 2020

Assignment of the human metabotropic glutamate receptor gene GRM7 to chromosome 3p26.1-->p25.2 by radiation hybrid mapping

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12 December 2020

Postsynaptic response kinetics are controlled by a glutamate transporter at cone photoreceptors

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12 December 2020

Expression of NMDAR1, GluR1, GluR7, and KA1 glutamate receptor mRNAs is decreased in frontal cortex of "neuroleptic-free" schizophrenics: evidence on reversible up-regulation by typical neuroleptics.

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12 December 2020

Human GluR6 kainate receptor (GRIK2): molecular cloning, expression, polymorphism, and chromosomal assignment

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12 December 2020

The lithium ion: a foundation for psychopharmacological specificity

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12 December 2020

Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics.

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12 December 2020

Genomic imprinting: parental influence on the genome

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12 December 2020

Family, genetic, and imaging studies of early-onset depression.

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12 December 2020

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain

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12 December 2020

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12 December 2020

Genetic and physical mapping of the GLUR5 glutamate receptor gene on human chromosome 21

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12 December 2020

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

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12 December 2020

The imprinted gene and parent-of-origin effect database

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12 December 2020

Enhanced LTP in mice deficient in the AMPA receptor GluR2.

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12 December 2020

Expression of 15 glutamate receptor subunits and various splice variants in tissue slices and single neurons of brainstem nuclei and potential functional implications

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12 December 2020

Evaluating the parent-of-origin effect in bipolar affective disorder. Is a more penetrant subtype transmitted paternally?

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12 December 2020

Chromosomal localization of gene for human glutamate receptor subunit-7

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12 December 2020

Molecular physiology of kainate receptors

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12 December 2020

Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia

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12 December 2020

Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.

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12 December 2020

Chromosomal localization of human glutamate receptor genes

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12 December 2020

Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotypes behavior and ataxia in rats

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12 December 2020

Phencyclidine impairs latent learning in mice: interaction between glutamatergic systems and sigma(1) receptors

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12 December 2020

The postsynaptic density at glutamatergic synapses

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12 December 2020

The N-methyl-D-aspartate receptor, synaptic plasticity, and depressive disorder. A critical review

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12 December 2020

Pore models for transporters?

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12 December 2020

A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia

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12 December 2020

Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors

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12 December 2020

Identification of the kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus

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12 December 2020

An integrated view of pathophysiological models of schizophrenia

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12 December 2020

A dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor.

1 reference

12 December 2020

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

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12 December 2020

Molecular cloning and chromosomal localization of the key subunit of the human N-methyl-D-aspartate receptor

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12 December 2020

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

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12 December 2020

Mammalian RNA-dependent deaminases and edited mRNAs

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12 December 2020

Mutation analysis of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) in schizophrenia

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12 December 2020

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

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12 December 2020

Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene.

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12 December 2020

Kainate receptors: knocking out plasticity

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12 December 2020

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

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12 December 2020

Assignment of the human metabotropic glutamate receptor gene GRM4 to chromosome 6 band p21.3 by radiation hybrid mapping

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12 December 2020

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

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12 December 2020

Molecular genetics of schizophrenia

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12 December 2020

Effects of dopaminergic drugs on phencyclidine-induced behavior in the rat

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12 December 2020

Phencyclidine-induced stereotyped behaviour and social isolation in rats: a possible animal model of schizophrenia.

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12 December 2020

Molecular cloning and chromosomal localization of one of the human glutamate receptor genes

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12 December 2020

Selective memory impairment by phencyclidine in rats.

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12 December 2020

Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia.

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12 December 2020

Molecular organization of the postsynaptic specialization

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12 December 2020

The tail suspension test: a new method for screening antidepressants in mice

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12 December 2020

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1.

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12 December 2020

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

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12 December 2020

Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): analysis of association with schizophrenia

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12 December 2020

Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice

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12 December 2020

Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. A quantitative in situ hybridization study.

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12 December 2020

Catching up on schizophrenia: natural history and neurobiology

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12 December 2020

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

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12 December 2020

Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A

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12 December 2020

Postsynaptic organization and regulation of excitatory synapses

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12 December 2020

Antidepressant effects of ketamine in depressed patients

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12 December 2020

Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors

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12 December 2020

PHARMACOLOGIC EFFECTS OF CI-581, A NEW DISSOCIATIVE ANESTHETIC, IN MAN.

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12 December 2020

Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia

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12 December 2020

Nucleus-specific expression of ionotropic glutamate receptor subunit mRNAs and binding sites in primate thalamus.

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12 December 2020

Observations on the psychotomimetic effects of Sernyl.

1 reference

12 December 2020

Effects of an AMPA receptor modulator on methamphetamine-induced hyperactivity in rats

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12 December 2020

D-cycloserine increases positive symptoms in chronic schizophrenic patients when administered in addition to antipsychotics: a double-blind, parallel, placebo-controlled study

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12 December 2020

The role of RNA editing in controlling glutamate receptor channel properties.

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12 December 2020

Metabotropic glutamate receptors: a structural view point.

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12 December 2020

Amphetamine response in rat after dopamine neurone destruction.

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12 December 2020

Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors

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12 December 2020

Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 2

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12 December 2020

The glutamatergic dysfunction hypothesis for schizophrenia

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12 December 2020

Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

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12 December 2020

Modifier genes in mice and humans

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12 December 2020

Refinement of map position of the human GluR6 kainate receptor gene (GRIK2) and lack of association and linkage with idiopathic generalized epilepsies

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12 December 2020

Glutamate signalling in non-neuronal tissues

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12 December 2020

A radiation hybrid map of 18 growth factor, growth factor receptor, hormone receptor, or neurotransmitter receptor genes on the distal region of the long arm of chromosome 5

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12 December 2020

Glutamate receptor expression in schizophrenic brain

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12 December 2020

Schizophrenia-associated chromosome 11q21 translocation: identification of flanking markers and development of chromosome 11q fragment hybrids as cloning and mapping resources.

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12 December 2020

Molecular mechanisms of calcium-dependent excitotoxicity

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12 December 2020

Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor

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12 December 2020

Excitatory amino acid transporters: a family in flux

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12 December 2020

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12 December 2020

COMPARISON OF AMPHETAMINE PSYCHOSIS AND SCHIZOPHRENIA.

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12 December 2020

Polymorphisms in the genes for mGluR types 7 and 8: association studies with schizophrenia

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12 December 2020

Dopamine receptor antagonists block amphetamine and phencyclidine-induced motor stimulation in rats

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12 December 2020

The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia

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12 December 2020

Neurotrophins and depression

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12 December 2020

Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

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12 December 2020

Definition of the phenotype

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12 December 2020

Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator.

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12 December 2020

Comparison of phencyclidine hydrochloride (Sernyl) with other drugs. Simulation of schizophrenic performance with phencyclidine hydrochloride (Sernyl), lysergic acid diethylamide (LSD-25), and amobarbital (Amytal) sodium; II. Symbolic and sequential

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12 December 2020

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

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12 December 2020

The changing landscape of ischaemic brain injury mechanisms.

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12 December 2020

Recent advances in the phencyclidine model of schizophrenia

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12 December 2020

Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems.

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12 December 2020

Properties of [3H]AMPA binding in postmortem human brain from psychotic subjects and controls: increases in caudate nucleus associated with suicide.

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12 December 2020

Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene

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12 December 2020

Mapping of the human NMDA receptor subunit (NMDAR1) and the proposed NMDA receptor glutamate-binding subunit (NMDARA1) to chromosomes 9q34.3 and chromosome 8, respectively

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12 December 2020

Antidepressant-like effect of brain-derived neurotrophic factor (BDNF).

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12 December 2020

Genomic imprinting: implications for human disease

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12 December 2020

Study of a new schizophrenomimetic drug; sernyl.

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12 December 2020

Anticipation, imprinting, trinucleotide repeat expansions and psychoses

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12 December 2020

The phenomenology of experimentally induced amphetamine psychosis--preliminary observations

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12 December 2020

Pentameric subunit stoichiometry of a neuronal glutamate receptor

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12 December 2020

Human metabotropic glutamate receptor 1: mRNA distribution, chromosome localization and functional expression of two splice variants

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12 December 2020

Identification of a site in glutamate receptor subunits that controls calcium permeability

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12 December 2020

Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence

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12 December 2020

Physical mapping of a glutamate receptor gene in relation to a balanced translocation associated with schizophrenia in a large Scottish family

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12 December 2020

Ionotropic glutamate receptor binding and subunit mRNA expression in thalamic nuclei in schizophrenia.

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12 December 2020

Genetics of schizophrenia and the new millennium: progress and pitfalls

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12 December 2020

NMDA receptor hypofunction model of schizophrenia

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12 December 2020

Increased dopamine transmission in schizophrenia: relationship to illness phases

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12 December 2020

Synergistic interactions between ampakines and antipsychotic drugs

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12 December 2020

Mutation analysis of the NMDAR2B (GRIN2B) gene in schizophrenia

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12 December 2020

The DARPP-32 knockout mouse

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12 December 2020

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

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12 December 2020

Glutamate receptors: brain function and signal transduction

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12 December 2020

Amphetamine selectively blocks inhibitory glutamate transmission in dopamine neurons

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12 December 2020

D-cycloserine added to clozapine for patients with schizophrenia

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12 December 2020

Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning.

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12 December 2020

Characterization of the human glutamate receptor subunit 3 gene (GRIA3), a candidate for bipolar disorder and nonspecific X-linked mental retardation

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12 December 2020

Ligands for glutamate receptors: design and therapeutic prospects

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12 December 2020

RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency

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12 December 2020

Nature, nurture and mental disorder: old concepts in the new millennium.

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12 December 2020

Cloned glutamate receptors

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12 December 2020

Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit

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12 December 2020

Quantitative immunocytochemistry of DARPP-32-expressing neurons in the rat caudatoputamen.

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12 December 2020

Molecular targets of lithium action

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12 December 2020

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

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12 December 2020

Abnormal excitatory neurotransmitter metabolism in schizophrenic brains

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12 December 2020

Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity.

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12 December 2020

Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice

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12 December 2020

The human glutamate receptor delta 2 gene (GRID2) maps to chromosome 4q22

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12 December 2020

Assignment of the gene GRM1 coding for metabotropic glutamate receptor 1 to human chromosome band 6q24 by in situ hybridization

1 reference

12 December 2020

Excitatory amino acid receptors and epilepsy.

1 reference

12 December 2020

Phencyclidine- and Dizocilpine-Induced Hyperlocomotion Are Differentially Mediated

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12 December 2020

The genes encoding the glutamate receptor subunits KA1 and KA2 (GRIK4 and GRIK5) are located on separate chromosomes in human, mouse, and rat

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12 December 2020

Dissociative anesthesia: further pharmacologic studies and first clinical experience with the phencyclidine derivative CI-581.

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12 December 2020

Learned helplessness and animal models of depression

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12 December 2020

Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels

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12 December 2020

Ca2+-Zn2+ permeable AMPA or kainate receptors: possible key factors in selective neurodegeneration

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12 December 2020

Hyperactivity and impaired response habituation in hyperdopaminergic mice

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12 December 2020

Identification of genes from a schizophrenia-linked translocation breakpoint region

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12 December 2020

Mice with genetically modified NMDA and AMPA receptors.

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12 December 2020

The forced swimming test as a model for core and component behavioral effects of antidepressant drugs.

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12 December 2020

The cellular neurobiology of depression

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12 December 2020

Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation

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12 December 2020

Structural determinants of ion flow through recombinant glutamate receptor channels

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12 December 2020

Imprinting mechanisms.

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12 December 2020

Open channel block of NMDA receptor responses evoked by tricyclic antidepressants

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12 December 2020

Alterations in the N-methyl-d-asparatate (NMDA) receptor complex in the frontal cortex of suicide victims

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12 December 2020

Identification of single nucleotide polymorphisms (SNPs) and other sequence changes and estimation of nucleotide diversity in coding and flanking regions of the NMDAR1 receptor gene in schizophrenic patients

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12 December 2020

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12 December 2020

Lack of evidence for close linkage of the glutamate GluR6 receptor gene with schizophrenia

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12 December 2020

Novel polymorphism in the gene region encoding the carboxyl-terminal intracellular domain of the NMDA receptor 2B subunit: analysis of association with schizophrenia

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12 December 2020

Calcium, glutamate, and amyotrophic lateral sclerosis: more evidence but no certainties

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12 December 2020

Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12

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12 December 2020

Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort.

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12 December 2020

Clozapine promotes approach-oriented behavior in male mice

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12 December 2020

Current and novel approaches to the drug treatment of schizophrenia

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12 December 2020

N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system

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12 December 2020

Knockout mice and dirty drugs. Drug addiction

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12 December 2020

Identifiers

DOI

10.1385/MN:25:2:191

1 reference

PubMed ID

11936559

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

11936559