Human immunodeficiency virus (HIV-1) infection selectively downregulates PD-1 expression in infected cells and protects the cells from early apoptosis in vitro and in vivo. (Q34591118)

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English	Human immunodeficiency virus (HIV-1) infection selectively downregulates PD-1 expression in infected cells and protects the cells from early apoptosis in vitro and in vivo.	scientific article

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6 January 2020

Human immunodeficiency virus (HIV-1) infection selectively downregulates PD-1 expression in infected cells and protects the cells from early apoptosis in vitro and in vivo (English)

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Europe PubMed Central

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6 January 2020

Velpandi Ayyavoo

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6 January 2020

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Narasimhan J Venkatachari

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6 January 2020

William G Buchanan

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25 April 2008

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6 January 2020

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3 August 2017

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6 January 2020

Apoptosis subversion: HIV-Nef provides both armor and sword

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Rapid expression of human immunodeficiency virus following activation of latently infected cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Could Nef and Vpr proteins contribute to disease progression by promoting depletion of bystander cells and prolonged survival of HIV-infected cells?

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Dynamics of cytokine expression in HIV productively infected primary CD4+ T cells

1 reference

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7 January 2021

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

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7 January 2021

Gene expression and viral prodution in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Split single-cell RT-PCR analysis of Purkinje cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Apoptosis as an HIV strategy to escape immune attack

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Turning on the off switch: regulation of anti-viral T cell responses in the liver by the PD-1/PD-L1 pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

The B7 family revisited

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Distinct mechanisms of CD4+ and CD8+ T-cell activation and bystander apoptosis induced by human immunodeficiency virus type 1 virions

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Apoptosis induced in HIV-1-exposed, resting CD4+ T cells subsequent to signaling through homing receptors is Fas/Fas ligand-mediated

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Mechanisms of HIV-1 to escape from the host immune surveillance.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

A novel mechanism for HIV1-mediated bystander CD4+ T-cell death: neighboring dying cells drive the capacity of HIV1 to kill noncycling primary CD4+ T cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Dendritic cells infected with vpr-positive human immunodeficiency virus type 1 induce CD8+ T-cell apoptosis via upregulation of tumor necrosis factor alpha.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

U937 cells overexpressing bcl-xl are resistant to human immunodeficiency virus-1-induced apoptosis and human immunodeficiency virus-1 replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

CD4+PD-1+ T cells acting as regulatory cells during the induction of anterior chamber-associated immune deviation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Alternative splice variants of the human PD-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Role of viral regulatory and accessory proteins in HIV-1 replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Human immunodeficiency virus (HIV) type 1 Vpr induces differential regulation of T cell costimulatory molecules: direct effect of Vpr on T cell activation and immune function

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Retroviral infection of non-dividing cells: old and new perspectives

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

Negative regulation of T-cell function by PD-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.03.015

7 January 2021

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