Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice (Q34597496)

3 August 2017

Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice (English)

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3 August 2017

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A D Dobrian

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3 August 2017

Q Ma

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3 August 2017

J W Lindsay

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3 August 2017

K A Leone

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3 August 2017

K Ma

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3 August 2017

J Coben

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3 August 2017

E V Galkina

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3 August 2017

J L Nadler

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3 August 2017

16 November 2010

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American Journal of Physiology - Endocrinology and Metabolism

3 August 2017

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3 August 2017

300

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3 August 2017

E410-21

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3 August 2017

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describes a project that uses

3 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3043624/fullTextXML

inferred from PubMed Central ID database lookup

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Sitagliptin (MK0431) inhibition of dipeptidyl peptidase IV decreases nonobese diabetic mouse CD4+ T-cell migration through incretin-dependent and -independent pathways

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection

7 July 2018

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The role of chemokines and chemokine receptors in diabetic nephropathy

7 July 2018

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Dual inhibition of dipeptidyl peptidase IV and aminopeptidase N suppresses inflammatory immune responses

7 July 2018

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7 July 2018

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Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity

7 July 2018

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

7 July 2018

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7 July 2018

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Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance

7 July 2018

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Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.

7 July 2018

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Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment

7 July 2018

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Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus

7 July 2018

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Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice.

21 January 2018

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Acute dipeptidyl peptidase-4 inhibition rapidly enhances insulin-mediated suppression of endogenous glucose production in mice.

21 January 2018

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Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

21 January 2018

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Increased number of islet-associated macrophages in type 2 diabetes.

21 January 2018

1 reference

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Soluble CD26/dipeptidyl peptidase IV enhances transendothelial migration via its interaction with mannose 6-phosphate/insulin-like growth factor II receptor

21 January 2018

1 reference

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DPP-IV inhibition enhances the antilipolytic action of NPY in human adipose tissue

21 January 2018

1 reference

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Differential antidiabetic efficacy of incretin agonists versus DPP-4 inhibition in high fat fed mice

21 January 2018

1 reference

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Dipeptidyl-peptidase 4 and attractin expression is increased in circulating blood monocytes of obese human subjects

21 January 2018

1 reference

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Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00463.2010

Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease

21 January 2018

1 reference

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Relationship between adipocyte size and adipokine expression and secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00463.2010

Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00463.2010

IL-12 serum levels in patients with type 2 diabetes treated with sulphonylureas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00463.2010

Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice.

21 January 2018

1 reference

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Presence and characterization of glucagon-like peptide-1(7-36) amide receptors in solubilized membranes of rat adipose tissue.

21 January 2018

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The Lee Obesity Index vindicated?

26 October 2018

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12 December 2020

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

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12 December 2020

CD26/dipeptidyl peptidase IV differentially regulates the chemotaxis of T cells and monocytes toward RANTES: possible mechanism for the switch from innate to acquired immune response

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12 December 2020

Age-dependent inability of the endocrine pancreas to adapt to pregnancy: a long-term consequence of perinatal malnutrition in the rat

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12 December 2020

Anthropometrical parameters and markers of obesity in rats

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12 December 2020

T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance

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12 December 2020

Adipose tissue lymphocytes and macrophages in obesity and insulin resistance: makers or markers, and which comes first?

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12 December 2020

IL6 as a mediator of insulin resistance: fat or fiction?

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12 December 2020

10.1152/AJPENDO.00463.2010

Identifiers

DOI

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3 August 2017

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3 August 2017

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